Tag Archives: Regenerative medicine

leukemias arise from changes that accumulate in blood stem cells

Imagine that a police bomb squad comes upon a diabolically designed bomb controlled by a tangled mass of different wires, lights and switches, some of which have a real function while others are decoys. The police don’t know how to begin defusing the bomb because they don’t know which parts are important. Then imagine the police discover the bomb-making factory and are able to see hundreds of these bombs at various stages of construction. With this information, they can reconstruct how the bomb was put together, and therefore how to disarm it.

For a team of researchers at
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Pfizer Acquires a Stem-Cell Therapy

Pfizer said Sunday that it was buying the rights to a somewhat controversial cell therapy from Athersys, a biotechnology company — a sign of big pharmaceutical companies’ growing interest in stem cells (…)

The relatively small payment reflects that “it’s really early for cell therapy and there’s more research to be done,” said Ruth McKernan, chief scientific officer of Pfizer Regenerative Medicine, a unit created by the company about 18 months ago to develop treatments based on stem cells (…)

Human Lung Stem Cell Discovered

For the first time, researchers at Brigham and Women’s Hospital (BWH) have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung including bronchioles, alveoli and pulmonary vessels.  This research is published in the May 12, 2011 issue of the New England Journal of Medicine.

“This research describes, for the first time, a true human lung stem cell.  The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the
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Europe’s first embryonic stem cell trial at Moorfields

British regulators have given Moorfields approval to begin trials using retinal cells derived from human embryonic stem cells (hESCs).

Twelve patients with Stargardt’s disease will have the cells injected into the eye. You can read more about the trial here.
Although there is great excitement about the trial, Julia knows that the initial phase will simply check safety (…)

“It would be marvellous if I could get some of my sight-loss reversed”, said Julia. “Even if it simply halts the deterioration, that would be great. And the real benefit would be for children. It could mean they don’t need to lose any
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Stem cells can speed new drugs discovery

Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus their efforts on cancer; the third will search for ways to accelerate the healing of large bone fractures.

The free screens will take place at the Choi Family Therapeutic Screening Facility, part of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. Andrew McMahon, director of the stem cell research center, is sponsoring the bone repair project, and Stephen Gruber, director of
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