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Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level. In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, MD, chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, has found that stem cells play an unexpected role in explaining what happens in bald scalp.
Using cell samples from men undergoing hair transplants, the team compared follicles from bald scalp and non-bald scalp, and found that bald areas had the same number of stem cells
“Now that we have identified SOX10 as an initiator of myelination, we can work on developing a viral or pharmaceutical approach to inducing it in MS patients,” says Fraser J. Sim, PhD, assistant professor and senior author of the paper.
Transcription factors are proteins or molecules that bind to DNA and alter which genes are turned on, or expressed.
“If we could create a drug that would switch on SOX10, that would be therapeutically important,” Sim explains.
Removing Barriers to MS Stem Cell Therapy
Targeting SOX10 offers hope for a viable stem cell treatment for MS.
Long seen as having dramatic potential for treating
CHA Bundang Medical Center has become the first in Asia (the second in the world) to confirm that the transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells is effective in treating age-related macular degeneration (AMD) and Stargardt disease (juvenile macular degeneration) without causing dangerous side effects. Hence CHA Bundang Medical Center is now on the fast track to developing the world’s first hESC-based therapeutic product.
A Korean research team, led by Professor Song Won-Kyung from CHA Bundang Medical Center, and CHA Biotech (a leading S. Korea-based biotechnology firm focused on stem cell therapies) jointly issued an
World stem cell leaders will converge on Promega’s BioPharmaceutical
Technology Center in Fitchburg, Wisconsin, on April 30 for the 9th
Annual Wisconsin Stem Cell Symposium: From Stem Cells to Blood.
Coordinated by the nonprofit BioPharmaceutical Technology Center Institute, the University of Wisconsin-Madison Stem Cell and Regenerative Medicine Center
and the UW-Madison Blood Research Program, this year’s symposium is
focused on how the stem cells that give rise to blood develop and
It will also look at the diversity of insights stem cell
studies have provided other fields.
Highlighted topics include genesis and regulation of progenitor cells
and hematopoietic stem cells, stem cell genomes/epigenomes, stem cell
microenvironment, and tumor initiating
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For some the stress of every day life can prove to be too much actually causing their hair to fall out. But now there’s an experimental treatment in the Bay area that may help your hair grow back regardless of why it fell out.
Russell Gibson is hoping it will work for him. Under the hot Florida sun each day he wears a black knit stocking cap pulled down low over his ears and his eyebrows. He spends hours working outside because he owns “Momma Gibbs Top Notch Boat Detail.” Seeing see him dressed in a t-shirt and