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The first patient in the landmark Pilot Investigation of Stem Cells in Stroke (PISCES) trial has been treated with neural stem cells. The study is the first fully regulated clinical trial of neural stem cell therapy for stroke. Investigators will evaluate the safety of ReNeuron cells in disabled ischemic stroke patients.
“This is a first in man safety study,” lead investigator Keith Muir, MD, from the University of Glasgow‘s Institute of Neuroscience and Psychology in Scotland, explained to Medscape Medical News. “We are looking at neurological effects — clinical and imaging — only as secondary goals.”
The stem cells
Fat around the waist is commonly seen as a contributing factor to heart attack. Ironically, a company is now testing whether adult stem cells from fat could help prevent long-term damage after a heart attack.
A new medical team is now investigating whether adult stem cells harvested from a person’s own fat, delivered shortly after a heart attack, could prevent some of the cardiac muscle damage that results from blocked arteries.
During a heart attack, blood vessels that deliver blood to the heart muscle are blocked. The lack of oxygen slowly kills the tissue. San Diego-based Cytori Therapeutics has developed
Osteoarthritis is a very common joint disorder. Due to age and normal wear and tear on the joints, the cartilage that protects the joint begins to break down, causing the bone to rub together which leads to pain and swelling in the joints. There is no cure for osteoarthritis, and up until now, many patients feel that surgery is their only option to manage the symptoms.
However, recently orthopaedic investigators have been studying the effects of periodic injections to the knee of stem cells from synovium, a thin membrane covering the inside of the joint. Nobutake Ozeki from Tokyo Medical
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A new research has suggested that cardiac stem cells – even in elderly and sick patients – could generate new heart muscle and vessel tissue and be used to treat heart failure.
Scientists surgically removed tissue from the muscular wall of the heart’s chambers in 21 patients.
They then isolated and multiplied the cardiac stem cells (CSCs) found there.
Most of the patients had ischemic cardiomyopathy (enlarged and weakened muscle due to coronary artery disease). Eleven also had diabetes. The average age of patients was about 65.
“Regardless of the gender or age of the patient, or of diabetes, we were
Until recently, when a patient suffering a heart attack arrived at a hospital, doctors could open the blocked blood vessel and restore blood flow to prevent further damage. But there was nothing they could do to reverse the harm already done. That damage — scarring that can kill up to 50 percent of the heart — leaves patients with difficulty breathing, loss of energy and the inability to do things such as walk up stairs. Some patients need transplants. And some end up with hearts so weak they die.
The solution: Now doctors can repair that damage. In