Researchers at UTHealth have demonstrated in rats that transplanting genetically modified adult stem cells into an injured spinal cord can help restore the electrical pathways associated with movement. The results are published in today’s issue of the Journal of Neuroscience.
In spinal cord injury, demyelination, or the destruction of the myelin sheath in the central nervous system, occurs. The myelin sheath, produced by cells called oligodendrocytes, wraps around the axons of nerves and helps speed activity and insulate electrical conduction. Without it, the nerves cannot send messages to make muscles move.
The research team, led by Qilin Cao, M.D., principal investigator
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Italian researchers have discovered new stem cells that could be potential sources of ‘spare’ neurons. A study carried out at the University of Verona has led to the discovery of Leptomeningeal Stem Cells (LeSC), a new population of stem cells located in the the meninges, which cover the entire central nervous system in mammals.
LeSCs are immature cells able to maintain themselves and differentiate into mature excitable neurons. This demonstrates that the brain has a greater regenerative capacity than what was believed until now. The results of the study, conducted on an animal model, were
Stem cell injections may be able to cure the crippling effects of multiple sclerosis, according to a study published today. Four out of five adults in the early stages of Muscular Sclerosis who were injected with stem cells taken from their own bone marrow experienced improvements in their conditions after three years, and the rest of the patients experienced a stabilization of their conditions. Dr. Doug Brown of the Muscular Sclerosis Society said that encouraging results have been obtained, and that it is exciting to see not only that the progression of the disability was stopped in