Tag Archives: National Institutes of Health

Baby monkeys born from stem cells

OHSU research demonstrates not all embryonic stem cells are equal; produces the world’s first primate chimeric offspring

Newly published research by scientists at Oregon Health & Science University provides significant new information about how early embryonic stem cells develop and take part in formation of the primate species. The research, which took place at OHSU’s Oregon National Primate Research Center, has also resulted in the first successful birth of chimeric monkeys — monkeys developed from stem cells taken from two separate embryos. The research will be published this week in the online edition of the journal Cell and will be
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Alzheimer’s disease potential treatment from neural stem cells

Frank LaFerla, left, Mathew Blurton-Jones and colleagues found that neural stem cells could be a potential treatment for advanced Alzheimer's disease

UC Irvine scientists have shown for the first time that neural stem cells can rescue memory in mice with advanced Alzheimer’s disease, raising hopes of a potential treatment for the leading cause of elderly dementia that afflicts 5.3 million people in the U.S.

Mice genetically engineered to have Alzheimer’s performed markedly better on memory tests a month after mouse neural stem cells were injected into their brains. The stem cells secreted a protein that created more neural connections, improving
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Fight baldness using Stem Cells

Baldness is an undesirable condition that afflicts both men and women, many of which have family members with significant hair loss. According to Health Day News, a new study of stem cells in mice shows promise for future treatments for people who battle hair loss.

The study was conducted on the fatty skin layers of mice by researchers at Yale University. Specifically, adipose precursor cells were found to spur new hair growth in mice, according to Health Day News.

Stem cells are present in hair follicles, which help generate hair growth. Health Day News explains that these cells are still present
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Correcting Sickle Cell Disease With Stem Cells

Using a patient’s own stem cells, researchers at Johns Hopkins have corrected the genetic alteration that causes sickle cell disease (SCD), a painful, disabling inherited blood disorder that affects mostly African-Americans. The corrected stem cells were coaxed into immature red blood cells in a test tube that then turned on a normal version of the gene.

The research team cautions that the work, done only in the laboratory, is years away from clinical use in patients, but should provide tools for developing gene therapies for SCD and a variety of other blood disorders.

In an article published online August 31 in
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Scientists watch stem cells at work regenerating tissue

Scientists have for the first time watched and manipulated stem cells as they regenerate tissue in an uninjured mammal, Yale researchers report July 1 online in the journal Nature.

Using a sophisticated imaging technique, the researchers also demonstrated that mice lacking a certain type of cell do not regrow hair. The same technique could shed light on how stem cells interact with other cells and trigger repairs in a variety of other organs, including lung and heart tissue.

“This tells us a lot about how the tissue regeneration process works,” said Valentina Greco, assistant professor of genetics and of dermatology at
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