Researchers have created mammalian cells containing a single set of chromosomes in research funded by the Wellcome Trust and EMBO. The technique should allow scientists to better establish the relationships between genes and their function.
Mammal cells usually contain two sets of chromosomes – one set inherited from the mother and one from the father. The genetic information contained in these chromosome sets helps determine how our bodies develop. Changes in this genetic code can lead to or increase the risk of developing disease.
To understand how our genes function, scientists manipulate the genes in animal models – such as the