The Pisa University Hospital has become part of the international network of hematopoietic stem cell transplant facilities (meaning they produce various blood components). The hospital was recently accredited by the Italian registry of bone marrow donors, which is part of the international network.
Pisa has become an important center for bone marrow collection for all potential donors in northwestern Italy.
On 20 April 2009, the first donation was carried out for a patient at the Udine University Hospital, and a second donation is being organized for a patient being treated at the Montpellier Hospital (France).
The hospital in Pisa received the
Stem cells of the aging bone marrow recycle their own molecules to survive and keep replenishing the blood and immune systems as the body ages, researchers at UC San Francisco (UCSF) have discovered.
The recycling process, known as autophagy, or self-eating, involves reusing molecules and the chemical energy obtained from these molecules to withstand the killing effect of metabolic stress that intensifies as the body ages.
The discovery, reported online Feb. 6 in the journal Nature, showed that autophagy allows stem cells to avoid the alternative response to stress, which is programmed cellular suicide, in which cells that aren’t
Researchers at the University of California, San Diego School of Medicine report that a protein called beta-catenin plays a critical, and previously unappreciated, role in promoting recovery of stricken hematopoietic stem cells after radiation exposure.
The findings, published in the May 1 issue of Genes and Development, provide a new understanding of how radiation impacts cellular and molecular processes, but perhaps more importantly, they suggest new possibilities for improving hematopoietic stem cell regeneration in the bone marrow following cancer radiation treatment.
Ionizing radiation exposure – accidental or deliberate – can be fatal due to widespread destruction of hematopoietic stem cells, the
World stem cell leaders will converge on Promega’s BioPharmaceutical
Technology Center in Fitchburg, Wisconsin, on April 30 for the 9th
Annual Wisconsin Stem Cell Symposium: From Stem Cells to Blood.
Coordinated by the nonprofit BioPharmaceutical Technology Center Institute, the University of Wisconsin-Madison Stem Cell and Regenerative Medicine Center
and the UW-Madison Blood Research Program, this year’s symposium is
focused on how the stem cells that give rise to blood develop and
It will also look at the diversity of insights stem cell
studies have provided other fields.
Highlighted topics include genesis and regulation of progenitor cells
and hematopoietic stem cells, stem cell genomes/epigenomes, stem cell
microenvironment, and tumor initiating
‘Yet again the Lazio region risks missing a chance to be at the cutting edge in the country for the therapeutic use of hematopoietic stem cells, a technique that is scientifically tested and proven in terms of its efficiency,’ said Luigi Canai, the President of the Lazio Health Commission, in a statement.
‘For days the media has been reporting important progress achieved in this field of research both abroad and in Italy. Regarding this subject, a year ago on February 19 2009, the commission chaired by me approved a unified text for a law that was later approved by