Tag Archives: Hematopoietic stem cell transplantation

Transplant with mismatched patient and donor

In an interview with ETHealthworld, Dr. Sachin Jadhav, Group In-charge – Haematology & Bone Marrow Transplantation, Gleneagles Global Hospitals, Bengaluru, talks about the innovations and challenges seen in this field.

What is Bone marrow transplant and how is India placed in this field? How do you see it globally?

Bone marrow transplant (BMT) is when we change the bone marrow. Bone marrow is what is present inside the bones and is a factory where all the blood cells are manufactured or created. Inside the bone marrow, we have stem cells which are like a seed that gives rise to red cells,
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The IOBA presents the results of clinical trials with cell therapy for corneal blindness

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Health Counselor Board, Javier Alvarez Guisasola, launched on Wednesday a clinical trial coordinated by Professor Margarita Calonge, IOBA’s on cell therapy applied to treat corneal blindness.
This study was coordinated by the IOBA and IBGM to demonstrate the long-term effectiveness of the epithelial stem cell transplantation of the cornea, previously cultivated to restore corneal blindness. Stem cells come from a healthy eye of the patient or family support.

Using the immune system to better stem cell transplant results

A novel therapy in the early stages of development at Virginia Commonwealth University Massey Cancer Center shows promise in providing lasting protection against the progression of multiple myeloma following a stem cell transplant by making the cancer cells easier targets for the immune system.

Outlined in the British Journal of Hematology, the Phase II clinical trial was led by Amir Toor, M.D., hematologist-oncologist in the Bone Marrow Transplant Program and research member of the Developmental Therapeutics program at VCU Massey Cancer Center. The multi-phased therapy first treats patients with a combination of the drugs azacitidine and lenalidomide. Azacitidine
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Understanding Stem Cells

“For centuries, scientists have known that certain animals can regenerate missing parts of their bodies. Humans actually share this ability with animals like the starfish and the newt. Although we can’t replace a missing leg or a finger, our bodies are constantly regenerating blood, skin, and other tissues.

The identity of the powerful cells that allow us to regenerate some tissues was first revealed when experiments with bone marrow in the 1950s established the existence of stem cells in our bodies and led to the development of bone marrow transplantation, a therapy now widely used in medicine.

This discovery raised
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New Stem Cells Therapy Treating Crohn’s Disease

Cellular therapy with stem cells is revolutionizing the focus of treatment of many serious diseases. Replacing the cells of damaged tissue with other new cells from the same patient is already a reality. This is the basis of cellular therapy and regenerative medicine, the latest great advance in biomedicine.

In this line, Hospital Clínic, Barcelona is exploring an innovative cellular therapy that uses stem cells to treat Crohn’s disease, a chronic genetic disease that affects 1% of the population in Spain and which has considerable impact on the quality of life of the patients. The procedure is based
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