Tag Archives: Doctor of Philosophy

I Want to Become a Medical Analyst… Any Suggestions on Why I Should Be MD, MD/PhD or PhD?

A Guest Post from Sandra Ochoa…

Sandra Ochoa

Well.. .my idea is always that prior you decide to set yourself on one of these paths do a little clinical shadowing and several lab research.

Some definitions first….
MD: Indicates Doctor of Medicine, a doctor’s education in medicine
PhD: Is the highest qualification obtained at a college or university, usually requiring 3 to 5 years of original analysis in a specific field of study.
MD/PhD: refers to an education consisting of both the medical training of a medical doctor (MD or DO) with the rigor of a scientific examiner (PhD)

You could also consider to get
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Researchers Connect New Genetic Signature to Leukemia

University of Rochester Medical Center scientists believe they are the first to identify genes that underlie the growth of primitive leukemia stem cells; and then to use the new genetic signature to identify currently available drugs that selectively target the rogue cells.

Although it is too early to attach significance to the drug candidates, two possible matches popped up: A drug in development for breast cancer (not approved by the Food and Drug Administration), and another experimental agent that, coincidentally, had been identified earlier by a URMC laboratory as an agent that targets leukemia cells.

Unusual ‘altruistic’ stem cell behavior with possible link to cancer

When most groups of mammalian cells are faced with a shortage of nutrients or oxygen, the phrase “every man for himself” is more apt than “all for one, one for all.” Unlike colonies of bacteria, which often cooperate to thrive as a group, mammalian cells have never been observed to help one another out. But a new study led by a researcher at the Stanford University School of Medicine has shown that certain human embryonic stem cells, in times of stress, produce molecules that not only benefit themselves, but also help nearby cells survive.

“Altruism has been reported among bacterial
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An easy manner to create heart muscle cells

Stanford cardiologist Joseph Wu, MD, PhD, and instructor Paul Burridge, PhD, have done something similar with stem cells. They’ve devised a way to create large numbers of heart muscle cells called cardiomyocytes from stem cells without using human or animal-derived products, which can vary in composition and concentration among batches. Their technique was published Sunday in Nature Methods. Wu, who is the director of the Stanford Cardiovascular Institute explained to me in an e-mail:

This technique solves an important hurdle for the use of iPS-derived heart cells. In order to fully realize the potential of these cells in drug screening
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A New Role for Old Sox

Understanding the genetic underpinnings of the biology of stem cells is crucial for their use in disease research and treatment. Scientists have identified a variety of genetic factors that maintain self renewal properties in embryonic, fetal, and adult stem cells. But whether these cell types are controlled by the same or different molecules is a persisting question.

Recent work from HSCI Principal Faculty Konrad Hochedlinger, PhD, begins to crack that mystery. Sox2 is a gene whose expression is required for maintaining pluripotency in early embryonic cells and regulating tissue development in the fetal stage. But until now, Sox2 expression had
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