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Health Counselor Board, Javier Alvarez Guisasola, launched on Wednesday a clinical trial coordinated by Professor Margarita Calonge, IOBA’s on cell therapy applied to treat corneal blindness.
This study was coordinated by the IOBA and IBGM to demonstrate the long-term effectiveness of the epithelial stem cell transplantation of the cornea, previously cultivated to restore corneal blindness. Stem cells come from a healthy eye of the patient or family support.
International Stem Cell Corporation announced that its Research and Development team has advanced its program to create a functional and transplantable human cornea by developing a new method to derive corneal endothelium-like cells from human pluripotent stem cells.
This work represents a significant step towards the creation of complete cornea tissue that can be used for transplantation and supports prior data showing indications of corneal endothelium generated by ISCO’s collaborators at Sankara Nethralaya Eye Hospital, India. Such cells by themselves may potentially promote wound healing and regeneration of the cornea and therefore could be used as a standalone medical treatment.
TONY EASTLEY: In a world first Melbourne researchers have rebuilt the surface of a human eye, using adult stem cells grown on a special type of contact lens.
One of the researchers is Karl Brown from the Centre for Eye Research Australia. He’s speaking with Ashley Hall.
KARL BROWN: We collected the adult stem cells from the very edge of the cornea. In the final version this could be the patient’s own eye if they have a good eye and an injured eye. Or it could be from material left over that is not used for a corneal transplant.
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Patients suffering from blindness now need not wait for donors as doctors have found a way to treat many with the stem cells derived from the cornea of a dead body.
Doctors at the AIIMS and a private clinic in the national capital are using corneal surface stem cells from a cadaver’s (dead person) eye for curing corneal injuries in many.
“We have used the corneal surface stem cells of cadaver’s eye for patients with corneal injury and have been able to correct many vision,” Dr Radhika Tandon, Associate Professor, Department of Opthalmology, AIIMS said, adding “this has been
Cultured stem cells from eyes helped improve the sight of eight patients with Limbal Stem Cell Deficiency, a painful, blinding disease, British doctors said.
The patients’ own corneal cells were cultured and used to reduce corneal cloudiness from the disease, The North East England Stem Cell Institute, Newcastle, England, reported in a release Thursday.