An experimental drug currently being tested against breast and lung cancer shows promise in fighting the brain cancer glioblastoma and prostate cancer, researchers at UT Southwestern Medical Center have found in two preclinical studies.
The drug’s actions, observed in isolated human cells in one trial and in rodents in the other, are especially encouraging because they attacked not only the bulk of the tumor cells but also the rare cancer stem cells that are believed to be responsible for most of a cancer’s growth, said Dr. Jerry Shay, professor of cell biology and a senior co-author of both papers. The
After extensively using stem cell therapy for treatment of leukemia, doctors are now pushing for using it to help cure solid tumours.
Doctors from various countries have congregated in the city to deliberate on the efficacy of using stem cells to treat the side-effects of chemotherapy, which, if given in high dosage, kills healthy cells as well.
“In several patients we have observed that the white blood cell count plummets following chemotherapy. This brings down the person’s resistance to infections. By transplanting stem cells we could counter that,” said Dr Ranjan Kumar Mohapatra, oncologist at Global Cancer Institute which is organising