Tag Archives: Cellular differentiation

Stem cells work together to make hair grow

Your hair may seem unwilling to cooperate some mornings, but at the root of each strand is a tiny partnership of stem cells that work very well together to make hair happen. New research from The Rockefeller University has elucidated how these adult stem cells communicate with each other to make hair grow and give it pigment.

“Deciphering the mechanisms behind stem cell differentiation advances our understanding of how adult stem cells can be used to maintain tissue integrity and heal wounds,” says Chiung-Ying Chang, a graduate student in the Laboratory of Elaine Fuchs, Rebecca C. Lancefield Professor
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Stem cell treatment for alcoholics

Of all the alcoholic liver disease patients thronging the out-patient departments of the Post Graduate Institute of Medical Education and Research (PGIMER), nearly 50% are from Punjab.

What draws them to this institute is the stem cell treatment offered to the severe alcoholic hepatitis that acts as a boon.

PGI is the only tertiary hospital in the region which caters to this end-stage liver disease from Punjab, Himachal, Haryana and Chandigarh.

The stem cell treatment reports 78% success in cases of severe alcoholic hepatitis. A report on the same had been published in the prestigious American journal of gastroenterology this month. Moreover,
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From Stem Cells to Lung Cells

Bronchi, bronchial tree, and lungs. (Photo credit: Wikipedia)

How do you grow stem cells into lungs? The question has puzzled scientists for years. First you need the right recipe, and it took BU researchers Darrell Kotton, Tyler Longmire, and Laertis Ikonomou seven years of trial and error and painstaking science to come up with it. “A lot had to happen to make a lung,” says Kotton. “It was a little more complicated than Julia Child’s ‘heat, eat, bon appetit.’”

Kotton is a School of Medicine associate professor of medicine and pathology and codirector of the Center for Regenerative Medicine (CReM),
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What Decides Neural Stem Cell Fate?

A gene called SOX2 acts as a stem cell gatekeeper – only cells expressing it have the potential to become neurons.

Early in embryonic development, the neural crest – a transient group of stem cells – gives rise to parts of the nervous system and several other tissues. But little is known about what determines which cells become neurons and which become other cell types. A team led by Dr. Alexey Terskikh at Sanford-Burnham Medical Research Institute (Sanford-Burnham) recently found that expression of a gene called SOX2 maintains the potential for neural crest stem cells to become neurons in the
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Israeli researchers discover method to neutralize tumor growth in embryonic stem cell therapy

Hebrew University of Jerusalem

Researchers at the Hebrew University of Jerusalem discovered a method to potentially eliminate the tumor-risk factor in utilizing human embryonic stem cells, said the university on Wednesday.
The researchers’ work paves the way for further progress in the promising field of stem cell therapy, said the press release of the university sent to Xinhua.

According to the release, human embryonic stem cells are theoretically capable of differentiation to all cells of the mature human body (and are hence defined as “pluripotent“).
This ability, along with the ability to remain undifferentiated indefinitely in culture, make regenerative medicine using human
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