Tag Archives: Cell biology

Macular Degeneration: Awesome results from Stem Cells

CHA Bundang Medical Center has become the first in Asia (the second in the world) to confirm that the transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells is effective in treating age-related macular degeneration (AMD) and Stargardt disease (juvenile macular degeneration) without causing dangerous side effects. Hence CHA Bundang Medical Center is now on the fast track to developing the world’s first hESC-based therapeutic product.

A Korean research team, led by Professor Song Won-Kyung from CHA Bundang Medical Center, and CHA Biotech (a leading S. Korea-based biotechnology firm focused on stem cell therapies) jointly issued an
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Stem Cells startup to fight ALS

USC Stem Cell researcher Justin Ichida has marshaled the expertise of pharmaceutical company Sanofi and startup DRVision Technologies, along with $1.5 million in federal funding, to find new drugs in the fight against amyotrophic lateral sclerosis, or Lou Gehrig’s disease.

ALS patients suffer from the death of the cells that transmit signals from the brain to the muscles, called motor neurons, leading to progressive paralysis and usually resulting in fatal respiratory failure within three to five years of diagnosis.

The three-year grant comes from the Department of Defense. Each year, the DoD funds two ALS Therapeutic Development Awards because military veterans
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Stem cell treatment for alcoholics

Of all the alcoholic liver disease patients thronging the out-patient departments of the Post Graduate Institute of Medical Education and Research (PGIMER), nearly 50% are from Punjab.

What draws them to this institute is the stem cell treatment offered to the severe alcoholic hepatitis that acts as a boon.

PGI is the only tertiary hospital in the region which caters to this end-stage liver disease from Punjab, Himachal, Haryana and Chandigarh.

The stem cell treatment reports 78% success in cases of severe alcoholic hepatitis. A report on the same had been published in the prestigious American journal of gastroenterology this month. Moreover,
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Gene key to develop stem cells

Researchers have found a gene that could be key to the development of stem cells — cells that can potentially save millions of lives by morphing into practically any cell in the body.

The gene, known as ASF1A, is at least one of the genes responsible for the mechanism of cellular reprogramming, a phenomenon that can turn one cell type into another, which is key to the making of stem cells.

Researchers at the Michigan State University analysed more than 5,000 genes from a human egg, or oocyte, before determining that the ASF1A, along with another gene known as OCT4 and
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Easier to develop life-saving stem cells

Not unlike looking for the proverbial needle in a haystack, a team of Michigan State University researchers have found a gene that could be key to the development of stem cells – cells that can potentially save millions of lives by morphing into practically any cell in the body.

The gene, known as ASF1A, was not discovered by the team. However, it is at least one of the genes responsible for the mechanism of cellular reprogramming, a phenomenon that can turn one cell type into another, which is key to the making of stem cells (…)

“This has the potential to
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