Adipose Stem Cell Heart Attack Trial Data Published in Journal of the American College of Cardiology; Cytori’s APOLLO Trial Demonstrated Safety & Feasibility and Improvements in Cardiac Function
Cytori Therapeutics announced today the publication of previously reported six-month outcomes from APOLLO, the Company’s European clinical trial evaluating adipose-derived stem and regenerative cells (ADRCs) in patients with acute myocardial infarction (heart attack or AMI), as Research Correspondence in the Journal of the American College of Cardiology. The APOLLO trial was a 14-patient, prospective, randomized, double-blind, placebo-controlled, feasibility trial (Phase I/IIA) evaluating autologous ADRCs extracted with the Company’s proprietary Celution® System for
A team of researchers from UCL has won a £500,000 grant to develop a synthetic artery that mimics a natural artery – and could revolutionise the treatment of coronary heart disease.
Professor Alexander Seifalian (UCL Surgery and Interventional Science) and Professor George Hamilton (UCL Surgery and Interventional Science & Royal Free Hospital) and their team will use the Wellcome Trust grant to take their work from the laboratory to a pre-clinical trial.
The team has been developing a new nanomaterial with mechanical properties similar to that of human arteries.
The nanomaterial’s inner surface has been modified to attract stem cells from blood
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Not all stem cells are ‘good’ at aiding the heart in repairing itself after a heart attack. Apparently, ‘baby cells’ present in human fat are the best equipped to perform this task and could be used in human testing by the end of 2009. “ We have seen that a simple stem cell transplant into a heart after a heart-attack is not sufficient. There are different types of stem cells that are better adapted to aiding the heart in the healing process. Instead of hematopoietic stem cells used in initial studies, mesenchymal
Scientists have taken the first steps toward producing the “heart patch,” a design for a medical implement used to repair damage from heart disease, a new study suggests.
Last week, researchers from Duke University presented the results of a study which, using mouse embryonic stem cells, examined the way these cells develop into heart muscle, HealthDay News reports (…)