Tag Archives: Cancer

German Study Discovers Stem Cell ‘Silent’ Reserves

Andreas Trumpp

Andreas Trumpp and his colleagues from the German Cancer Research Center have recently spoken about a “silent reserve” of stem cells, wondering what type of medical impact the discovery made in Heidelberg of “dormant stem cells” could have.

Usually, dormant bone marrow cells activate and multiply only in a crisis or emergency to react to serious cellular loss due to a virus or hemorrhage. When their work is done, they return to a dormant stage. This withdrawal phase keeps them protected from mutations, cellular toxins, and other dangerous substances, since the cells do not divide
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ITALY – Stem Cells. Zebrafish Provides Hope For Costello Syndrome Patients

Mental retardation, altered facial characteristics, and heart problems are all problems suffered by children affected by Costello syndrome, a genetic disease that is being studied by researchers in Milan at the Italian Foundation for Cancer Research (FIRC) Institute of molecular oncology (IFOM) using the zebrafish as a model.

The cause of the disease – explained the scientists in the January issue of ‘Disease Models & Mechanisms’ monthly magazine – is a mutation of the Ras gene, the same alteration observed in 20pct of tumors. One out of every five cases of cancer and the rare genetic disease have a common
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RP hospitals now providing stem-cell treatments

The flattening of the world’s economy has spawned a new trend in the local medical-tourism industry: Foreigners are starting to come to the Philippines because of the country’s ever-growing availability of cheap but reliable regenerative or stem-cell treatments.
Dr. Samuel Bernal, consultant on regenerative medicine for the Medical City, said some hospitals in the Philippines are starting to gain vigor in stem-cell treatments. Patients treated last year reached over 100 in number.

“Ours [Philippines] is cheaper compared to other developed and developing nations,” Bernal told the BusinessMirror in a phone interview on Monday after a briefing with the media on “Bioregenerative
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Stem Cell–Associated Proteins Can Identify Origins of Pediatric Tumors

Research has indicated that certain sarcomas come from the mesenchymal stem cells. However, expression of neural stem cells has been noted in others. Identifying and isolating mesenchymal stem cells and neural stem cells relies on finding specific proteins expressed by both types.

In this study, eight different markers representing proteins associated with these two types of stem cells were applied to the 81 tumors. Through cluster analysis, the researchers organized the data into groups showing similar patterns. Two major subgroups of pediatric sarcomas emerged

Stem cells can speed new drugs discovery

Three teams of USC stem cell researchers have won a coveted prize — the opportunity to test 3,000 drug candidates or chemicals for the potential to help patients. Two teams will focus their efforts on cancer; the third will search for ways to accelerate the healing of large bone fractures.

The free screens will take place at the Choi Family Therapeutic Screening Facility, part of the Eli and Edythe Broad Center for Regenerative Medicine and Stem Cell Research at USC. Andrew McMahon, director of the stem cell research center, is sponsoring the bone repair project, and Stephen Gruber, director of
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