Tag Archives: Breast cancer

Isolating breast stem cells speeds cancer research

LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

“What we’ve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,” says Peter C. Gray, a staff scientist in Salk’s Clayton Foundation Laboratories for Peptide Biology, who
Read More…

POTENTIAL NEW “TWIST” IN BREAST CANCER DETECTION

December 4, 2009- Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called “Twist” may be the proverbial red flag that can accurately distinguish stem cells that drive aggressive, metastatic breast cancer from other breast cancer cells.

Building on recent work suggesting that it is a relatively rare subgroup of stem cells in breast tumors that drives breast cancer, scientists have surmised that this subgroup of cells must have some very distinctive qualities and characteristics.