TaiGen Biotechnology Co., Ltd. announced today that in a phase 1 study in healthy volunteers TG-0054, a chemokine receptor CXCR4 antagonist, was well tolerated and rapidly mobilized stem cells and endothelial progenitor cells from bone marrow into peripheral blood. The number of CD34+ stem cells in circulation after one dose of TG-0054 was equal or higher than reported cell numbers needed for stem cell transplantation in cancer patients. The observed AEs were all mild and transient. A phase 2 study in stem cell transplantation for multiple myeloma, non-Hodgkin lymphoma and Hodgkin disease patients is currently being initiated (…)
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Before going ahead and explaining the possibilities that are on the verge of development based on the regenerative capabilities of a stem cell, let us first understand what a stem cell is actually. Stem cells are the basic group of cells that have the extremely potent capability of regenerating themselves. The process through which they regenerate themselves is known as mitotic cell division and after the division, the previously unspecialized cells turn into specialized cells for specific organs through cellular differentiation.
These cells are not found in unicellular organisms, but are found in varying quantities within all multi
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Embryonic stem cells (ESC) can survive even when inserted into chains of polymers, in a process in which they are “weaved” into artificial and flexible tissues able to adapt to various types of transplants. In an innovative technique, stem cells could be used in the future to produce artificial organs, say researchers at University College London.
The technique was described in a study, published in Integrative Biology. It implements other research to shape living cells into engineered tissues, including a technique which would print a live tissue using an ink printer, which would substitute normal ink
Michela and Alessandro from Sassari (Sardinia) are Kevin‘s parents, a 2 age old child suffering from spastic quadriparesis and optic nerve hypoplasia (blindness). Since he was born he endured 4 surgeries: kidneys, heart, bladder tumor and genital rebuilding.
Then Bangkok. And now the parents are hoping.
But Kevin is not alone because there are more than 100 Italian citizens treated with chinese cord stem cells in Bangkok’s hospital.
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Sheng Ding, the leader of a group of researchers at the Scripps Research Institute of the La Jolla University in California, spoke about using chemistry-related techniques to obtain pluripotent stem cells from a miniscule section of skin at Milan University in a conference on stem cells.
Experts were able to cause some skin cells in mice to regress to their embryonic state by injecting four proteins into an adult mouse without performing any sort of DNA manipulation. A technique that, according to their idea, could be safer than techniques based on genetic manipulation. The