Tag Archives: USC Davis School of Gerontology

USC Stem Cell researchers share a vision of the future

What do former British Prime Minister Tony Blair and singer Will.i.am have in common? They both attended this year’s Milken Institute Global Conference, where USC Stem Cellresearchers offered a glimpse into the future of regenerative medicine (…)

During a well-attended panel session about regenerative medicine, Paula Cannon, associate professor at the Keck School of Medicine and principal investigator with USC Stem Cell, talked about genetically modifying hematopoietic or blood-forming stem cells to cure HIV/AIDS (…)

She also emphasized the recent progress made in the field of stem cell biology as a whole (…)

Starving causes restoration of stem cells in immune system

In the first evidence of a natural intervention triggering stem cell-based regeneration of an organ or system, a study shows that cycles of prolonged fasting not only protect against immune system damage — a major side effect of chemotherapy — but also induce immune system regeneration, shifting stem cells from a dormant state to a state of self-renewal.

In both mice and a Phase 1 human clinical trial, long periods of not eating significantly lowered white blood cell counts. In mice, fasting cycles then “flipped a regenerative switch,” changing the signaling pathways for hematopoietic stem cells, which are responsible for
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