Tag Archive for 'University of Utah'

Published Study Shows Adult Stem Cells Help Multiple Sclerosis

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A stem cell research study showing that Adult Stem Cells taken from a patient’s fat and then implanted back into that patient, helps improve their Multiple Sclerosis. The research study documented 3 case studies of Multiple Sclerosis patients.

Case Studies of Multiple Sclerosis Patients Implanted with Fat Stem Cells

Case Study #1- 50 year old man with Relapse-remitting MS:

Before the Stem Cell Therapy:

  • Multiple Seizures
  • Sexual Dysfunction
  • Significant Memory Loss
  • Taking Multiple Medications- Solu-Medrol, Baclofen,
    Provigil, Tegretol, Trileptal, Tysabri, Vitamins, Omega-3 and Zanaflex

After the Fat Stem Cells were implanted:

  • No more seizures
  • Improved Sexual Function
  • Improved Memory
  • OFF ALL MEDICATIONS

Case Study #2- 32 year old man with Relapsing-remitting MS

This patient reported after the stem cell therapy and treatment that he now has:

  1. Better Balance and Coordination
  2. His Depression is gone
  3. Significantly improved overall condition

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Three Heart Disease Patients Improve After Adult Stem Cell Treatment

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Dr. Amit Patel of the University of Utah is reporting that 3 out of 3 heart disease patients have improved in the initial stages of his stem cell research trial in which the cardiomyopathy patients had their own Adult Stem Cells injected back into their heart in a minimally invasive surgical procedure.

Dr. Patel presented the initial data at the International Society for Cellular Therapy (ISCT) annual meeting in San Diego, California.  The clinical research trial is treating heart patients with both ischemic cardiomyopathy and non-ischemic dilated cardiomyopathy and then injecting them with their own Adult Stem Cells.  There is a control group in the study as well. Translation-  some patients are not getting the benefit of the stem cells and receive a placebo.

Initial Data of Patients Treated with Adult Stem Cells

Here are the results so far (from the stem cell article)-

  • 3 cardiomyopathy patients who received their own stem cells were followed up at 3 months.  They all improved on their New York Heart Failure Classes- all 3 going from a Class III to a Class II.  In contrast 2 out of the 3 who didn’t get stem cells , did NOT improve.
  • Overall quality of life scores (Minnesota Living with Heart Failure Questionnaire) improved in all 3 patients who received the stem cell therapy.  The physical and emotional well-being of all the patients who received the treatment also improved.  There was no consistent trend in the control group (the group that didn’t get the stem cells)

Millions Would Benefit With Use of Own Stem Cells

While these are positive results and I am happy for these patients, there are thousands of cardiomyopathy patients who are not able to receive this stem cell treatment.  Dr. Kit Arom of Vescell in Thailand, a former associate of Dr. Patel, is now treating these exact same patients with their own stem cells and none of these dilated cardiomyopathy and heart attack patients are in a “control” group ie. they are getting the exact same procedure and getting their own Adult Stem Cells that Dr. Patel’s trial is doing (sucessfully).

Dr. Kit Arom has been treating heart disease patients in Thailand since 2005 with this exact same procedure- and the USA has just done 3??? Is something wrong here?

The Debate on Stem Cell Research – A Smokescreen?

While there is the endless debate on Embryonic Stem Cell research vs. Adult Stem Cell research, is the debate just some  clever smokescreen thrown up by the drug companies, FDA, and cardiologists, none of whom will benefit from heart (or name your disease)  patients using their own Adult Stem Cells to help themselves?  Is this stem cell debate just a means to slow down the use of the patient’s own cells?  Remember, there are no side effects from using your own stem cells, either they help (most of the time) or they don’t (no harm done).

Are people getting so caught up on the stem cell research issue that we are ignoring the patients who are in need of help right now?  Are we so intent on 100% “cures” that we ignore stem cell treatments that are not “cures”, but do indeed help improve the quality of lives of the majority of patients right NOW.   I’m sure the patients who improved in the stem cell heart study above are very happy with their results.  Are their hearts 100% perfect now?  No,  it wasn’t a “cure”.  Does that mean it isn’t good enough?

Why do we have to go for the homerun on every at bat, when a patient would be grateful for a single or double?  Would Michael J Fox be happy if his Parkinson’s symptoms subsided for 5 years like this gentleman?  Or, I’m sure the heart patients are pleased that instead of getting short of breath from getting the mail, that they are probably now able to walk around their local mall with their loved ones.

I see endless articles and letters to the editor that support this research or that research, but rarely do I see an article or letter promoting USING the only treatment that works now- Adult Stem Cells.  In the end, with all this hoopla, we end up forgetting about what should be the reasons for the debates and research in the first place- the patients.

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ITALY – Rome, Universita’ Cattolica, lecture on intestinal and pancreatic stem cells

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SALT LAKE CITY, UT - OCTOBER 8:  University of...
Image by Getty Images via Daylife

“The role of BMI1 in adult intestinal and pancreatic exocrine stem cells” is the name of the opening lecture of the 2008-2009 Biology Lectures promoted by the Institute of General Pathology at Università Cattolica in Rome, headed by Professor Tommaso Galeotti. The seminar will take place on Wednesday, March 18 at 3:00pm, in the Aula Moscati at the University in Rome (Biology Institute, Largo F. Vito 1), and will be led by Eugenio Sangiorgi, a researcher at the Institute of Medical Genetics for the university, and by the post-doctoral fellowship in the laboratory of Mario Capecchi, 2007 Nobel prize for Medicine winner, from the University of Utah in Salt Lake City.

The young geneticist from Cattolica University, a student of Professor Giovanni Neri, will present the results of his work, which demonstrate the presence of multipotent stem cells in the intestine and pancreas in adult animals, the premise for a better understanding of neoplastic transformation processes, and for interesting innovative treatments that could be potentially important for intestinal tumors and for diabetes mellitus.

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