Any legislation that slows human embryonic stem cell research is likely to also seriously harm the study of induced pluripotent stem cells, according to a new study by researchers at the Stanford University School of Medicine, the Mayo Clinic and the University of Michigan.
The finding strongly refutes the idea that embryonic stem cell research can be abandoned in favor of the less-controversial iPS cells, which are derived from adult human tissue.
“If federal funding stops for human embryonic stem cell research, it would have a serious negative impact on iPS cell research,” said Stanford
Shelley Brown was pointing toward a life of cutting-edge stem cell research. Then one day in 2010, she says, she encountered the divine.
“Something was moving, and I thought I must have hit the petri dish by accident,” said Brown, who had been trying to direct a set of stem cells toward bone cells during her Ph.D. work in biomedical engineering at the University of Michigan. “When I looked closer under the microscope, I realized the cells were beating. They had spontaneously differentiated into electrically coupled, beating heart cells. That’s when I felt at the mercy of God, and that’s
Neuralstem Inc. has received the green light to begin the first human stem cell trial to treat Amyotrophic Lateral Sclerosis (ALS), often referred to as Lou Gehrig’s disease. The company’s stock soared on the news.
Neuralstem has only received approval for the first stage of the trial that would consist of 12 patients who will receive stem cell injections in the lumbar area of the spinal cord.
Neuralstem said the trial will be under the direction of principal investigator Dr. Eva L. Feldman, Director of the University of Michigan Health System ALS Clinic and the Program for Neurology Research & Discovery.
University of Michigan researchers have proven that a special surface, free of biological contaminants, allows adult-derived stem cells to thrive and transform into multiple cell types. Their success brings stem cell therapies another step closer.
To prove the cells’ regenerative powers, bone cells grown on this surface were then transplanted into holes in the skulls of mice, producing four times as much new bone growth as in the mice without the extra bone cells.
An embryo’s cells really can be anything they want to be when they grow up: organs, nerves, skin, bone, any type of human cell. Adult-derived “induced” stem
Researchers at the University of Michigan Comprehensive Cancer Center have found that a cancer gene linked to aggressive spread of the disease promotes breast cancer stem cells. The finding implies a new way to target the behavior of these lethal cells.
The finding involves the cancer gene RhoC, which has previously been shown to promote metastasis of many types of cancer. RhoC levels increase as breast cancer progresses and high levels of RhoC are associated with worse patient survival.
Cancer stem cells are the small number of cells within a tumor that are believed to fuel the tumor’s growth