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After the decision of the United States to remove the ban preventing stem cell researchers from using public funding for experiments, legislators in South Korea have been put under pressure by scientists who have been aspiring to do experiments on stem cells from cloned human embryos.
Up until a few weeks ago the National Bioethics Committee continued to postpone a decision on the matter, but now thanks to the American president, it is increasingly probable that at most, by the end of April, researchers of the Cha Medical Institute of Seoul will be able to resume
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A team of researchers lead by Dr Thimios Mitsiadis at the University of Zurich, Switzerland, has identified a gene responsible for the formation of enamel, which is the key component of the teeth. The experiments were accomplished in mice carrying a deletion of the transcription factor Tbx1, a gene that plays a principal role in several human malformations (heart, thymus, parathyroid, face, and teeth) associated to the DiGeorge syndrome.
“Subjects afflicted by DiGeorge syndrome exhibit teeth with enamel defects. We have demonstrated that a direct link between impaired Tbx1 function and enamel defects exists. Enamel forms via the
Stem cell therapy represents a promising strategy in regenerative medicine. However, cells need to be carefully preserved and processed before usage. In addition, cell transplantation carries immunogenicity and/or tumourigenicity risks.
Mounting lines of evidence indicate that stem cells exert their beneficial effects mainly through secretion (of regenerative factors) and membrane-based cell–cell interaction with the injured cells. Here, we fabricate a synthetic cell-mimicking microparticle (CMMP) that recapitulates stem cell functions in tissue repair.
CMMPs carry similar secreted proteins and membranes as genuine cardiac stem cells do. In a mouse model of myocardial infarction, injection of CMMPs leads to the preservation of viable
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Stem cells injected into the eyes of mice with defective corneas returned the corneas to a more normal appearance, a new study has found.
Researchers hope the procedure might one day be in humans. About 40,000 such transplants are done each year in the United States.
“The stem cells took the scar-like matrix, remodeled it and made it more like normal,” said senior investigator James Funderburgh, an associate professor of ophthalmology at the University of Pittsburgh. “We were surprised and delighted.”
A report on the study is in the April 9 online edition of the journal Stem Cells.
It may seem surprising, but more than 1,700 dogs in the USA with arthritis have already been treated with their own stem cells.
Remember the saying “Patient Heal Thyself?” We all — human and animals — carry around a stem cell repair kit that is used every day in helping heal the minor bumps, bruises, cuts and more serious injuries.
These stem cells are called “adult” stem cells and are found throughout the body. They sit there waiting for the signal that they are needed and they rush to the scene of the injury and begin the healing process.
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