Tag Archives: Tissue (biology)

Stem Cells “food”

Revolutionary as they may be, stem cells cannot escape the need for food. And until now, that food has represented a costly part of developing stem cells.

But that is about to change. The East Greenbush-based Neural Stem Cell Institute has developed a new substance that will substantially lower development costs.

“Stem cells are unstable,” as Christopher Fasano, the Institute’s director of research and development, says. He explains that they need a constant supply of food and a substance called a “growth factor,” or they start developing into different types of body tissues on their own, and cease being useful to
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Stem Cells: breakthrough in artificial human organ transplant

Researchers for the first time have been able to demonstrate fully functional complex tissues of human organs i.e. intestines, obtained using stem cell technology, which finds applications in laboratory research as well as medical purposes. The paper was published in the journal Nature.

“This is the first study to demonstrate that human pluripotent stem cells in a petri dish can be instructed to efficiently form human tissue with three-dimensional architecture and cellular composition remarkably similar to intestinal tissue,” said Dr. James Wells, a leading researcher at the Medical Center’s Children’s Hospital of Cincinnati. “The hope is that our ability
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Stem cells overcome major cause of blindness

Researchers have identified a way to enhance regrowth of human corneal tissue to restore vision, using a molecule that acts as a marker for hard-to-find limbal stem cells.

This work, a collaboration among the Harvard-affiliated Massachusetts Eye and Ear/Schepens Eye Research Institute, Boston Children’s Hospital, Brigham and Women’s Hospital, and the VA Boston Healthcare System, holds promise for burn patients, victims of chemical injury, and others with damaging eye diseases.

The research, published this week in the journal Nature,is also one of the first examples of constructing a tissue from an adult-derived human stem cell.

Limbal stem cells reside in the eye’s
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Stanford’s Irving Weissman on the (lost?) promise of stem cells

Stanford stem cell researcher Irving Weissman, MD, published an article in Cell Stem Cell today discussing barriers to stem cell research:

While I am usually an optimist, I must admit that there is a possibility that we will continue to be in the Dark Ages of medicine for quite some time. I fear that therapies using purified tissue and organ-specific stem cells – the only self-renewing cells in a tissue or that can regenerate that tissue or organ for life – will remain elusive.

Weissman, who directs Stanford’s Institute for Stem Cell Biology and Regenerative Medicine, goes on to cover the
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New kidney tissues from stem cells

Researchers in Japan said on Wednesday they have succeeded in growing human kidney tissue from stem cells for the first time in a potential breakthrough for millions with damaged organs who are dependent on dialysis.

Kidneys have a complex structure that is not easily repaired once damaged, but the latest findings put scientists on the road to helping a diseased or distressed organ fix itself.

Kenji Osafune of Kyoto University said his team had managed to take stem cells — the “blank slates” capable of being programmed to become any kind of cell in the body — and nudge them specifically
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