Tag Archives: Tissue (biology)

Stem cells can be harvested long after death

Some stem cells can lay dormant for more than two weeks in a dead person and then be revived to divide into new, functioning cells, scientists in France said.
The research, published in the journal Nature Communications, unlocks further knowledge about the versatility of these cells, touted as a future source to replenish damaged tissue.

“Remarkably, skeletal muscle stem cells can survive for 17 days in humans and 16 days in mice, post mortem well beyond the 1-2 days currently thought,” they said in a statement.
The stem cells retained their ability to differentiate into perfectly functioning muscle cells, they found.

“This discovery
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A New Role for Old Sox

Understanding the genetic underpinnings of the biology of stem cells is crucial for their use in disease research and treatment. Scientists have identified a variety of genetic factors that maintain self renewal properties in embryonic, fetal, and adult stem cells. But whether these cell types are controlled by the same or different molecules is a persisting question.

Recent work from HSCI Principal Faculty Konrad Hochedlinger, PhD, begins to crack that mystery. Sox2 is a gene whose expression is required for maintaining pluripotency in early embryonic cells and regulating tissue development in the fetal stage. But until now, Sox2 expression had
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Stem cells may help heal damaged arteries

In a new study, researchers have for the first time demonstrated that baboon embryonic stem cells can be programmed to completely restore a severely damaged artery.

These early results show promise for eventually developing stem cell therapies to restore human tissues or organs damaged by age or disease.

“We first cultured the stem cells in petri dishes under special conditions to make them differentiate into cells that are the precursors of blood vessels, and we saw that we could get them to form tubular and branching structures, similar to blood vessels,” John L. VandeBerg, chief scientific officer from Texas Biomedical Research
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NSF award to stem cells engineering

From a simple blood draw, Krishanu Saha, a researcher in WID’s BIONATES research group and assistant professor of biomedical engineering, could enable doctors to create stem cells to develop drugs personalized to their patients.

As part of his $400,000 National Science Foundation CAREER Award over the next five years, Saha will focus on improving the process to directly evolve DNA sequences and proteins in human stem cells.

Stem cells have the potential to develop into many different cell types, which makes them ideal for a variety of medical research projects.

The evolution of synthetic DNA sequences in human stem cells could catalyze
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New kidney tissues from stem cells

Researchers in Japan said on Wednesday they have succeeded in growing human kidney tissue from stem cells for the first time in a potential breakthrough for millions with damaged organs who are dependent on dialysis.

Kidneys have a complex structure that is not easily repaired once damaged, but the latest findings put scientists on the road to helping a diseased or distressed organ fix itself.

Kenji Osafune of Kyoto University said his team had managed to take stem cells — the “blank slates” capable of being programmed to become any kind of cell in the body — and nudge them specifically
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