“Latest Stem Cells News”

Joseph Wagner sees most cell-therapy companies offering little more than a bag of cells.
His company will give the bag a little direction.

Cell Targeting is developing technology that can point stem cell therapies to specific areas of the body. Among the many challenges in cell therapy is direction: not enough of the stem cells are getting to the tissues that needs treatment (…)

Currently a stem cell therapy can help different parts of the body. That attracts more customers, but doesn’t do much when the company wants to differentiate its product and charge a different price.

A stem cell therapy tweaked by Cell Targeting can become unique because it can be directed to different areas of the body to treat different afflictions, Wagner said.

“We make them distinct by our delivery,” Wagner said. “We have the ability to make those bags of cells into unique cell-therapy products.”

Cell Targeting’s product is a peptide, a tiny piece of protein, that coats stem cells and guides them to damaged tissue. The coating peels away like paint after it gets to its target and allows the therapy to do its work (…)

But Cell Targeting’s biggest competitor may be science itself and the research underway to better understand how stem cells work. It’s likely that stem cells on their own can find their way “home” to specific tissues, Gerson said.

“We just don’t know what those Velcro connections are,” Gerson said.

Wagner said the idea that stem cells head home is a bit of “voodoo.” Only a single-digit percentage of cells return to their point of origin — and there’s no evidence they return in a larger percentage to damaged tissues, he said. Also, Wagner pointed out that in many cases, cell therapy companies don’t want stem cells to go “home” but instead to another tissue that the stem cell can also heal (…)

from http://www.medcitynews.com/index.php/2009/09/cell-targeting-ready-to-bring-purpose-to-stem-cell-therapy/

Recent stem cell research studies using Adult Stem Cells to treat heart diseases such as congestive heart failure and heart attacks have made the news recently.  And on the surface, these adult stem cell success stories of heart attack victims making amazing recoveries in these research clinical trials is wonderful news indeed.

New Research Trials for Heart Attack Victims

For example, at the Texas Heart Institute, John Hartman who had suffered a heart attack recently had his own stem cells implanted into his heart muscle in a new stem cell research trial.

From the stem cell article:

Dr. Jim Willerson President, Texas Heart Institute, said, “We think the improvement we see is largely from the blood flow increase salvaging the cells that are reversibly injured, allowing them to function normally.”

“That reflects in the patient being able to do better, walk further, breathe better,” said Dr. Emerson Perin St Luke’s, THI Cardiologist.

Stem Cell Trial for Congestive Heart Failure

Also, in another stem cell research trial at Vanderbilt, an unnamed 65 year old congestive heart failure patient was treated using his own Adult Stem Cells again.   Dr. David Zhao, director of the cath lab there said “The patients who stand to benefit from this approach include those whose coronary arteries are so diseased that nothing else could be done,”

What About Heart Disease Patients Who Can’t Get Adult Stem Cells?

However, the headlines don’t mention the millions who are suffering and dying after having heart attacks (1.25 million per year in the United States) and are in congestive heart failure and don’t have the opportunity to receive adult stem cell treatment because the FDA has classified a patient’s own stem cells as a drug- thus slowing down progress and starving heart patients of a “drug” with no side effects or ethical issues and only has upside.

For every Barry Brown or Kenneth Milles, heart attack victims who were lucky enough to get into a US stem cell research clinical trial using their own stem cells, there are millions of heart disease patients who do not have that opportunity. And for that, we have the FDA to blame.

And that is only addressing adult stem cell therapy for heart disease………what about the hundreds of other conditions that can be helped or improved by Adult Stem Cells?

Sad.

For more information on clinical research trials in the United States, go to the Clinical Trials website – www.clinicaltrials.gov

Sierra Rose Hill, a young girl from Australia with cerebral palsy who was already helped by Adult Stem Cells is off again to Germany for a 2nd stem cell treatment.  Sierra went to Germany in December, 2008 for the therapy with her own stem cells and it paid big dividends.  We first covered Sierra here in this stem cell post in March

Adult Stem Cells Successful First Time- Now Going for Two!

As a result of the first stem cell treatment, Sierra got “looser” in her limbs, more flexibility and a better ability to control her tongue. Sierra responded so well to her own Adult Stem Cells that her parents have now raised enough money to return to Germany for more stem cell therapy.

Stem Cell Research Documentary

Sierra and her parents are leaving for Germany on June 25th for the treatment. However, this time, they will have company. Pia Niebel is producing a documentary called ‘Little Mountains’ about Sierra and in Pia’s words:

‘Little Mountains’ is an intimate portrayal of an Australian family’s struggle with cerebral palsy and the risks and choices associated with emerging stem cell technologies. It is a character driven documentary that enquires about the current status of adult stem cell treatment and why it is not available in Australia.

Adult Stem Cells Available to Help In Australia? No

I often moan on how adult stem cells are not available in the United States.  However, of course, there are people everywhere who have diseases and conditions that adult stem cells could help.  There is no reason why Australia shouldn’t be making a person’s own stem cells available for treatment as well.

And as Sierra’s father said once  “If that (stem cell treatment) was available in Australia, at an affordable price, if it was at a hospital from a professional service, that could make such a huge difference to people with cerebral palsy and various other conditions,” he said. “I know they want to do their clinical trials. But they are providing this service already around the world. I would like to see it here.”

Pia is looking for funding to help her produce this Adult Stem Cell research documentary which would be a nice step in the right direction in getting Adult Stem Cell treatment approved in Australia.  If you would like to help Pia get the word out, you can contact her here:
Pia Niebel
LIGHT PUZZLE MEDIA
Creative Producer
mobile +61 (0)4 388 77 183
Email: happy@pia.net.au

Here is a preview of Pia’s stem cell research documentary featuring the lovely Sierra and her parents:

A group of patients who have been helped by stem cell research using Adult Stem Cells have formed a group called the Stem Cell Awareness Association.  This group is growing fast with prospective stem cell patients and even US doctors joining the movement.   They will be holding a Stem Cell Awareness rally this Saturday, June 13th, 2009 in Denver.

Making Others Aware of the Benefits of Adult Stem Cells

The Stem Cell Awareness Association was formed by Carol Peterson.  Carol is the grandmother of Cameron Peterson, a young toddler who was blind from Optic Nerve Hypoplasia, but now can see thanks to stem cell therapy in China using Adult Stem Cells from cord blood.

Educated Freedom of Choice

Carol says the mission of the Stem Cell Awareness Association can be summarized  in four simple words, “Educated Freedom of Choice.

“Our group is mainly made up of patients who have experienced what is really available in other countries and while we don’t want to exert influence over other patients’ decisions, we do want to make them aware that what is available in the U.S. is not representative of what is available throughout the world.”

US Medical Establishment Protecting Patients Or Are They More Worried About Lawsuits and Reputations?

David Aldrich, a spinal cord injury patient who has improved tremendously after his stem cell treatments in China also weighs in on the topic-

“I am worn out from dealing with a medical establishment that does not provide me with the best treatment available and oftentimes tries to stop people like me from seeking treatment abroad under the guise of protecting me,” said Aldrich. “My short-term goal is to let people know that there is help available, no matter what your physician says. But my real goal is focused on bringing people together to figure out what can be done so I don’t have to go abroad for my next treatment.”

If you guessed that David was referring to the American medical establishment not providing him with the best treatment available,  you would be correct.

Too Much Focus On Stem Cell Research and Not Enough Focus On Helping Patients Now With Adult Stem Cells?

While America focuses on “research” using billions of taxpayer dollars, other countries are using Adult Stem Cells now and actually helping patients improve their lives.

For example, take Shel Morse, the mother of Macie Morse, who was legally blind from her optic nerve hypoplasia, but CAN NOW DRIVE!  after receiving adult stem cell therapy in China, she has her say -

“Macie’s journey to stem cells started when she turned 15 and asked for a driving permit. It wasn’t even an option with her current vision, not to mention the fact a vision teacher of hers had stated it was never going to be possible and we should just face reality. At that point I knew that it was my mission to let people know that they don’t necessarily have to live with the diagnosis their local doctors give them.

“Macie’s doctors not only criticized the companies we told them about but actively discouraged us from help overseas – help that they could not offer. The reason why I got behind this organization and decided to set up this event in Denver is because the patients need to join together to have a voice. Our medical society needs to get serious about real health care; we cannot rely on our current system – it is broken. U.S. doctors and scientists need to focus on doing what is necessary to help patients instead of their reputations and how they can make money.”

What else can I say?  Carol, David and Shel said it perfectly.    See the full stem cell press release here

If you are in the Denver area on Saturday, go check them out, you may learn something and for sure you will meet some brave individuals-

All patients who are considering stem cell treatments or have already had stem cell treatments are welcome to join the next Stem Cell Awareness Rally:
Location: Denver, Colorado
Place: Stella’s Coffee House
Date: June 13th, 2009
Time: 2 pm

In the Dominican Republic, Dr. Zannos Grekos, a stem cell research doctor, is now helping patients with heart disease and lung diseases with their own Adult Stem Cells as reported on CNN in a special research report.

Adult Stem Cells Helping Heart Disease and Lung Disease

In the last 18 months, Dr. Grekos and his company Regenocyte have treated more than 100 patients for either heart diseases such as congestive heart failure, coronary artery disease, heart attacks, and angina and lung diseases such as pulmonary hypertension, emphysema and COPD.

The story features Barbara McKean of Naples, Florida. Barbara was suffering from the lung disease, COPD and was treated with her own stem cells.

From the stem cell article:
“Right away, the next morning, I felt a sense of well-being that I hadn’t felt in a long, long time,” McKean said.

“I know that I am living proof that this does work,” she added. “I know that.”

His Eyes Are Wide Shut

Check out this quote from the chief medical officer of the American Lung Association-

The chief medical officer of the American Lung Association, Dr. Norman Edelman, said he does not doubt the sincerity of patients who believe they have been helped by stem cell therapy. But he added, “There’s an enormous placebo effect in almost all of these cases.”

So Dr. Edelman sees a woman, Barbara McKean, featured previously here,  who was on oxygen 24/7 walking around with a cannister and now, after stem cell treatment, is completely off oxygen and he thinks it is the placebo effect? Ridiculous.

Luckily, Barbara’s doctor does not intentionally close his eyes to the obvious:

McKean’s family physician, Dr. Robert Folsom, confirmed to CNN that she had been suffering for many years from an advanced state of COPD, an incurable lung disease. Folsom told CNN he was “quite incredulous” after seeing her condition improve.

Folsom, who said he has been McKean’s family physician for many years, disputed any suggestion that her apparent recovery stemmed from a “placebo effect” — an improvement sometimes seen in patients who are given an inert substance in clinical trials.

“I know about the placebo effect, and her improvement does not seem to be a result of that,” he said.

Stem Cell Therapy- Documenting Results

Dr. Grekos is documenting research data  from his patients treated with their own stem cells and wishes to present it to the FDA at the end of this year.

In the past few days, another stem cell research doctor, Dr. Roberto Fernandez Vina, also just presented his results of his stem cell research data for COPD and Emphysema at the annual International Society for Stem Cell Research annual meeting.

And Dr. Grekos had a parting shot for the “experts” who always try to downplay any adult stem cell success story:

He shrugs off the criticism from people who doubt his claims, saying he — and not they — are on medicine’s cutting edge.

Stem cell experts who reject his methods “need to be better educated,” he said.

original post by Don Margolis

In a recent published clinical stem cell research study, adult stem cells were shown to help delay Amyotrophic Lateral Sclerosis (ALS) progression and improve an ALS patient’s quality of life. This research study was believed to be the first published study comparing ALS patients who had their own stem cells injected into their brain vs a control group.

Thank you very much to ALS Worldwide for providing us with this exciting stem cell research breakthrough in humans- not mice! Any clinical studies like this in the United States? I can’t hear you….

Without further ado- here is the published stem cell research study on ALS: Stem-cell transplantation into the frontal motor cortex in amyotrophic lateral sclerosis patients

Summary of Adult Stem Cell Therapy for ALS Study

This summary is provided by the good people at ALS Worldwide as well as they went to observe this tremendous stem cell treatment using Adult Stem Cells!

HOSPITAL SAN JOSE TECNOLOGICO DE MONTERREY STEM CELL PROCEDURE

The initial two year clinical test study results of the stem cell procedure instituted by Hospital San Jose Tecnologico de Monterrey, was published in Cytotherapy, February, 2009. Positive results were confirmed through both clinical observation and MRI tractography. It is considered by many within the international neurological community to be the foremost procedure available for minimizing or abrogating ALS symptoms and extending the lifespan of ALS patients. The procedure is a state of the art use of autologous CD-133 (+) stem cells injected into the frontal cortices for the effective replacement of motor neurons.

Representing the ALS WORLDWIDE patient community, we were at Hospital San Jose Tecnologico de Monterrey in Mexico from June 6-14 to observe the hospitalization and procedures for the first two international patients being provided this stem cell therapy. In a sentence, the official message delivered is clear: “This stem cell procedure is not a cure. We offer nothing more than the promise of stability and extended life expectancy. The opportunity, however, exists for improvement. “

Process of Stem Cells for Lou Gehrig’s Disease

The stem cell preparation procedure is sophisticated and complicated but in the simplest terms, the patient’s blood is purified, extracted and cleansed. Stem cells are extracted and then the one kind of stem cell that can be best coaxed into becoming a neuron is injected into two places in the brain. The patient experiences no pain and very little discomfort during the procedure. A mild sedative is provided and within hours, the patient is back in his or her room, enjoying dinner.

The team effort at Hospital San Jose Tecnologico de Monterrey embraces a cooperative spirit that pervades every aspect of their efforts. Patients and their families are treated with the highest level of concern, respect and support. The hospital itself resembles the finest hotel and provides exemplary care. A more detailed, scientific explanation of the Monterrey experience is currently being prepared and will be posted to ALS WORLDWIDE within the next week.

I hope to post these updates on this breakthrough in stem cell research as well.

original post by Don Margolis