“Latest Stem Cells News”

Progress has been made against strokes thanks to stem cells. British researchers, thanks to these cells, have managed to repair brain tissue damaged by a stroke. The study, financed by the research council on biological and biotechnological sciences of the United Kingdom, was published in Nature Biomaterials. The team from the Institute of Psychiatry at the University of Nottingham, used a biodegradable polymer called Plga to build a scaffold for neural cells.

Using these they filled the cavity left by a stroke. This allows, explained Mike Modo, psychiatrist at King’s College in London and coordinator of the study, “stem cells to create connections with the other cells, contributing to the re-stabilization of the damaged tissue”. One of the main obstacles for scientists has been overcome in this way: normally, stem cells do not find any support in the cerebral area affected

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Stem Cell Research Study Reveals Stroke Patients Helped by Own Stem Cells

A new stem cell research study/trial recently completed shows that implanting a person’s own Adult Stem Cells helps stroke patients overcome partial paralysis. Dr. Kameshwar Prasad of the All India Institute of Medical Sciences (AIIMS) will present his stem cell study at the European Stroke Research Conference in May, 2009.

Stroke Victims Own Adult Stem Cells Used

In the stem cell study that took place in New Delhi, India, 12 stroke victims had their own stem cells implanted within 1 month after a stroke. Also, 3 stroke patients were used as a control group and were not given any stem cells.

Process of Stem Cells for Stroke

1. Adult Stem Cells extracted from patient’s bone marrow
2. Stem Cells are then purified
3. Patient’s own stem cells are then reintroduced intravenously into the antecubital vein (in the forearms, near the elbow)
4. Stem Cells migrate to area of injury (in this case- the brain)
5. Adult Stem Cells enhance repair process and reduce brain damage

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Roland "Bud" Henrich, 61, was the first stroke patient to be enrolled in a Phase I trial using his own stem cells.

For the first time in the United States, a stroke patient has been intravenously injected with his own bone marrow stem cells as part of a research trial at The University of Texas Medical School at Houston.
Sean Savitz, M.D., assistant professor of neurology at The University of Texas Medical School at Houston, leads a first-of-its-kind bone marrow stem cell therapy study for stroke patients.

Roland “Bud” Henrich, 61, was transferred to Memorial Hermann – Texas Medical Center on March 25 after suffering a stroke while working on his farm in Liberty. He arrived too late to receive tissue plasminogen activator (tPA), the only treatment for ischemic strokes. He became the first patient in the trial.

The Phase I safety trial, funded with a pilot grant from The National Institutes of Health and support from the Notsew Orm Sands Foundation, will enroll nine more patients who have suffered a stroke and can be treated with the stem cell procedure within 24 to 72 hours of initial symptoms.

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