“Latest Stem Cells News”

Stem Cell researchers at Cambridge and Edinburgh have discovered a promising stem cell therapy for multiple sclerosis. While much work is still needed to translate the discovery into an effective treatment, this breakthrough provides a promising road map towards a cure.

A video story featuring the SCI’s Robin Franklin can be viewed on the BBC News website.

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Viet Nam’s National Hospital of Pediatrics in Ha Noi this morning announced the initial success of its first stem cell therapy treatment of epidermolysis bullosa (EB), making it only the second medical institution in the world to successfully treat this genetic skin disease in this manner.

Children with EB lack a protein that anchors the outer layer of skin to the body, resulting in very fragile skin that peels off with minor friction or trauma. They suffer painful wounds and infections which eventually are fatal.

The four-year-old boy who underwent the bone marrow transplant received tissue taken from his sister, aged 10, on September 16, to stimulate the production of healthy skin cells.

Nguyen Viet Anh had a severe form of EB, which caused his toes to stick to each other and skin to peel off the inside of his mouth, said hospital director Nguyen Thanh Liem.

“It is a very complicated technology but we are happy that the donor’s bone marrow tissue has taken in his body,” he said.

Anh’s white cell count has increased to a normal level 40 days after the transplant from almost zero. The area of affected skin is now only 7 per cent of the body, a big progress from 23 per cent before the transplant.

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Dr. Neil Riordan presents data on human umbilical cord-derived stem cell treatments. Dr. Riordan is Founder of the Stem Cell Institute in Panama City, Panama.

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Prominent Texan, Dusty Durrill, discusses his improvements after undergoing stem cell therapy for osteoarthritis at the Stem Cell Institute in Panama City, Panama.

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Cultured stem cells from eyes helped improve the sight of eight patients with Limbal Stem Cell Deficiency, a painful, blinding disease, British doctors said.

The patients’ own corneal cells were cultured and used to reduce corneal cloudiness from the disease, The North East England Stem Cell Institute, Newcastle, England, reported in a release Thursday.

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Scripps Research Institute scientists have offered new hope for parents whose children suffer from the rare genetic disorder ‘cystinosis’ by showing through an experiment on mice that stem cell transplantation can successfully correct the defect (…)

In the study, the researchers used bone marrow stem cell transplantation to address symptoms of cystinosis in a mouse model (…)

In the new study, the researchers found that transplanted bone marrow stem cells carrying the normal lysosomal cystine transporter gene abundantly engrafted into every tissue of the experimental mice (…)

“The results really surprised and encouraged us. Because the defect is present in every cell of the body, we did not expect a bone marrow stem cell transplant to be so widespread and effective,” says Cherqui.
Cherqui said that adult bone marrow stem cell therapy is particularly well suited as a potential treatment for cystinosis because these cells target all types of tissues.

In addition, stem cells reside in the bone marrow for the duration of a patient”s life, becoming active as needed, a particular benefit for a progressive disease like cystinosis. The study has been published in the journal Blood.

from http://www.newkerala.com/nkfullnews-1-114380.html

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