Tag Archives: Spinal cord

London – Researchers find safer way to make stem cells

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Researchers said on Sunday they had found a safer way to transform ordinary skin cells into powerful stem cells in a move that could eventually remove the need to use human embryos.
It is the first time that scientists have turned skin cells into induced pluripotent stem cells or iPS cells — which look and act like embryonic stem cells — without having to use viruses in the process.
The new method also allows for genes that are inserted to trigger cell reprogramming to be removed afterwards.
Stem cells are the body’s master cells, producing all the body’s tissues and
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Stem Cells Regenerate Severe Spinal Cord Injury

In a study at the University of California, San Diego and VA San Diego Healthcare, researchers were able to regenerate “an astonishing degree” of axonal growth at the site of severe spinal cord injury in rats. Their research revealed that early stage neurons have the ability to survive and extend axons to form new, functional neuronal relays across an injury site in the adult central nervous system (CNS).

The study also proved that at least some types of adult CNS axons can overcome a normally inhibitory growth environment to grow over long distances. Importantly, stem cells across species
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Stem cells heal damaged brain

Although embryonic stem (ES) cells have been induced to differentiate into diverse neuronal cell types, the production of cortical projection neurons with the correct morphology and axonal connectivity has not been demonstrated.

Here, we show that in vitro patterning is critical for generating neural precursor cells (ES-NPCs) competent to form cortical pyramidal neurons.

GREAT BRITAIN – Stem Cells Repair Heart and Bone Damage

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A research group at Imperial College London has designed a new treatment able to significantly improve the body’s capacity to repair damage caused by a heart attack or bone fracture. The new therapy, described in Cell Stem Cell, ‘fools’ the spinal cord inducing it to ’overproduce’ stem cells which repair damaged tissues in the body. Researchers hope to test the treatment on animals by the end of the year. If testing is successful, the next step will be to experiment on human beings attempting to induce them to use their own stem cells
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DaVinci: Stem cell treatment helped spinal cord patients

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Following up on eight acute and chronic spinal cord injury patients who were injected with bone marrow stem cells two years ago, researchers say that the therapy proved safe and effective in improving their quality of life.

DaVinci Biosciences undertook the study in Ecuador and have now issued a follow-up report claiming that MRIs have revealed “noticeable morphological changes within the spinal cord after administration of autologous bone marrow derived stem cells.” There was no tumor formation, increased pain or deterioration of function following administration of the stem cell treatment.