Children with progeria, a rare disorder that causes premature aging, die in their teens of ailments that are common in octogenarians: heart failure and stroke. Kan Cao, a University of Maryland assistant professor of cell biology and molecular genetics, urgently wants to help find a cure. Cao and her colleagues have taken a big step in that direction, showing that a toxic protein destroys muscle cells inside the patients’ arteries. The researchers suspect the damaged arteries are more prone to failure.
The researchers conducted their experiments on smooth muscle cells that they genetically engineered. “This gives us a very good
Scientists, including an Indian researcher, have found a previously unknown stem cell which is the real culprit behind heart attacks, a landmark finding which, they say, could revolutionize treatments for the cardiac disease.
Until now, it has been thought that vascular health problems were triggered by smooth muscle cells, but a team at the University of California in Berkeley identified a previously unknown stem cell, which causes the arteries to harden when it multiplies.
The groundbreaking work is set to completely change how heart attacks and strokes are treated, dramatically cutting the number of deaths, the researchers said.
“For the first time,