Tag Archives: School of Biological Sciences

Human Neural Stem Cells Restore Memory in Models of Alzheimer’s Disease

StemCells Inc. announced preclinical data demonstrating that its proprietary human neural stem cells restored memory and enhanced synaptic function in two animal models relevant to Alzheimer’s disease (AD). The data was presented today at the Alzheimer’s Association International Conference 2012 in Vancouver, Canada.

The study results showed that transplanting the cells into a specific region of the brain, the hippocampus, statistically increased memory in two different animal models. The hippocampus is critically important to the control of memory and is severely impacted by the pathology of AD. Specifically, hippocampal synaptic density is reduced in AD and correlates with memory loss.
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StemCells awarded $100,000 grant to develop Alzheimer’s therapy

StemCells, Inc. announced today that the California Institute of Regenerative Medicine (CIRM) has approved the Company’s application for a “Disease Team Therapy Development Planning Award.”

The grant, totaling approximately $100,000, will help fund the Company’s plans to develop its proprietary human neural stem cell product, HuCNS-SC(R) cells, in Alzheimer’s disease by enabling the Company and its collaborators at the University of California, Irvine, to prepare and submit an application for a “Disease Team Therapy Development Research Award.”

The CIRM has indicated that each Research Award will be up to $20 million, payable over four years, to fund preclinical and IND-enabling activities
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