Flip past the big photo on page 65 of beaming software magnate Bill Gates and New York Mayor Michael Bloomberg and there, on page 67, beside a picture of U.S. president Barack Obama, is a microscope image of a cell.
That induced embryonic stem cell has vaulted Toronto scientist Andras Nagy into this high-flying company in Scientific Magazine’s inaugural Top 10 awards for work in science-related endeavours.
“It’s an enormous honour and a recognition of the science we do in the lab, and what we do in Mount Sinai, and what we do in Toronto and what we do in Canada,”
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Discovery sheds new light on the process of stem cell generation, and will help promote safer stem-cell based studies and future clinical trials.
Dr. Andras Nagy’s laboratory at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and Dr. Timo Otonkoski’s laboratory at Biomedicum Stem Cell Center (University of Helsinki), as well as collaborators in Europe and Canada have identified genetic abnormalities associated with reprogramming adult cells to induced pluripotent stem (iPS) cells. The findings give researchers new insights into the reprogramming process, and will help make future applications of stem cell creation and subsequent use safer.