Using new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and potentially treat the disease early (…)
Currently, over 1.1 percent of the world’s population has schizophrenia, with an estimated three million cases in the United States alone.
The economic cost is high: in 2002, Americans spent nearly $63 billion on treatment and managing disability. The emotional cost is higher still: 10 percent of those with schizophrenia are driven to commit suicide by the
LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.
“What we’ve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,” says Peter C. Gray, a staff scientist in Salk’s Clayton Foundation Laboratories for Peptide Biology, who
Scientists have for the first time grown embryos that contain a combination of pig and human stem cells, in a step toward one day growing transplantable organs, a study said on Thursday.
However, the research remains at a very early stage and proved more difficult than expected, the researchers reported in the peer-reviewed journal Cell.
“This is an important first step,” said lead investigator Juan Carlos Izpisua Belmonte, a professor in the Salk Institute of Biological Studies’ Gene Expression Laboratory.
“The ultimate goal is to grow functional and transplantable tissue or organs, but we are far away from that.”
Scientists implanted adult human
A recent report published in the medical journal Stem Cell Reports, sheds light on breakthrough research regarding the use of thyroid cells derived from stem cells for new therapies. Scientists at Boston University’s School Medicine led the work.
They have pinpointed a means of efficiently engineering thyroid cells by way of stem cells that will eventually help analyze and treat thyroid diseases (…)
The breakthrough described above was discovered after studies were performed on mice. Stem cells are valued as they can mature into an array of different cell types.
Led by researchers at the University of California, San Diego School of Medicine, scientists have, for the first time, created stem cell-derived, in vitro models of sporadic and hereditary Alzheimer’s disease, using induced pluripotent stem cells from patients with the much-dreaded neurodegenerative disorder.
“Creating highly purified and functional human Alzheimer’s neurons in a dish – this has never been done before,” said senior study author Lawrence Goldstein, PhD, professor in the Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute Investigator and director of the UC San Diego Stem Cell Program. “It’s a first step. These aren’t perfect models.