Tag Archives: Salk Institute for Biological Studies

Stem Cells help polio-affected man walk

(…) At the age of 29, Bhoir underwent a surgery to correct deformity in his legs. Although the limb length improved, there was no change in muscle strength. He then decided to consult Dr Pradeep Mahajan to be treated by stem cell therapy.

“A personalized treatment protocol was prepared comprising of 1 session of autologous cellular therapy combined with physiotherapy, yoga and diet modifications.

Stem cell-gene therapy technique cures genetic disease in human cell line

Image by JohnnyRokkit via Flickr

Scientists are one step closer to creating a gene therapy/stem cell combination to combat genetic diseases. With work, this research may lead to not only curing the disease, but also repairing the damage left behind.

While gene therapy is a burgeoning field that has shown great results in treating genetic disorders, many of those diseases leave behind heavily damaged tissue that the body is unable to repair. So even if the disease is completely eradicated, quality of life may not necessarily improve, and without help, health can still continue to deteriorate.

Since stem cell research began, there
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Stem cells study aims to foresee schizophrenia

Using new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and potentially treat the disease early (…)

Currently, over 1.1 percent of the world’s population has schizophrenia, with an estimated three million cases in the United States alone.

The economic cost is high: in 2002, Americans spent nearly $63 billion on treatment and managing disability. The emotional cost is higher still: 10 percent of those with schizophrenia are driven to commit suicide by the
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Isolating breast stem cells speeds cancer research

LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

“What we’ve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,” says Peter C. Gray, a staff scientist in Salk’s Clayton Foundation Laboratories for Peptide Biology, who
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Transplants: human-pig embryos from stem cells

Scientists have for the first time grown embryos that contain a combination of pig and human stem cells, in a step toward one day growing transplantable organs, a study said on Thursday.

However, the research remains at a very early stage and proved more difficult than expected, the researchers reported in the peer-reviewed journal Cell.

“This is an important first step,” said lead investigator Juan Carlos Izpisua Belmonte, a professor in the Salk Institute of Biological Studies’ Gene Expression Laboratory.

“The ultimate goal is to grow functional and transplantable tissue or organs, but we are far away from that.”

Scientists implanted adult human
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