Tag Archives: Salk Institute for Biological Studies

New Thyroid Therapies by Stem Cells

A recent report published in the medical journal Stem Cell Reports, sheds light on breakthrough research regarding the use of thyroid cells derived from stem cells for new therapies. Scientists at Boston University’s School Medicine led the work.

They have pinpointed a means of efficiently engineering thyroid cells by way of stem cells that will eventually help analyze and treat thyroid diseases (…)

The breakthrough described above was discovered after studies were performed on mice. Stem cells are valued as they can mature into an array of different cell types.

Alzheimer’s Neurons From Pluripotent Stem Cells

Led by researchers at the University of California, San Diego School of Medicine, scientists have, for the first time, created stem cell-derived, in vitro models of sporadic and hereditary Alzheimer’s disease, using induced pluripotent stem cells from patients with the much-dreaded neurodegenerative disorder.

“Creating highly purified and functional human Alzheimer’s neurons in a dish – this has never been done before,” said senior study author Lawrence Goldstein, PhD, professor in the Department of Cellular and Molecular Medicine, Howard Hughes Medical Institute Investigator and director of the UC San Diego Stem Cell Program. “It’s a first step. These aren’t perfect models.
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Stem Cells help polio-affected man walk

(…) At the age of 29, Bhoir underwent a surgery to correct deformity in his legs. Although the limb length improved, there was no change in muscle strength. He then decided to consult Dr Pradeep Mahajan to be treated by stem cell therapy.

“A personalized treatment protocol was prepared comprising of 1 session of autologous cellular therapy combined with physiotherapy, yoga and diet modifications.

Stem cells study aims to foresee schizophrenia

Using new stem cell technology, scientists at the Salk Institute have shown that neurons generated from the skin cells of people with schizophrenia behave strangely in early developmental stages, providing a hint as to ways to detect and potentially treat the disease early (…)

Currently, over 1.1 percent of the world’s population has schizophrenia, with an estimated three million cases in the United States alone.

The economic cost is high: in 2002, Americans spent nearly $63 billion on treatment and managing disability. The emotional cost is higher still: 10 percent of those with schizophrenia are driven to commit suicide by the
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Isolating breast stem cells speeds cancer research

LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

“What we’ve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,” says Peter C. Gray, a staff scientist in Salk’s Clayton Foundation Laboratories for Peptide Biology, who
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