Tag Archives: Regenerative medicine

Genetic abnormalities associated with the creation of stem cells

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Discovery sheds new light on the process of stem cell generation, and will help promote safer stem-cell based studies and future clinical trials.

Dr. Andras Nagy’s laboratory at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital and Dr. Timo Otonkoski’s laboratory at Biomedicum Stem Cell Center (University of Helsinki), as well as collaborators in Europe and Canada have identified genetic abnormalities associated with reprogramming adult cells to induced pluripotent stem (iPS) cells. The findings give researchers new insights into the reprogramming process, and will help make future applications of stem cell creation and subsequent use safer.
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Stanford creates first PhD program in stem cell science

Stanford University’s Faculty Senate today approved the creation of what officials believe is the first PhD program devoted solely to stem cell science in the nation and, perhaps, the world. The new doctoral program in stem cell biology and regenerative medicine is also the first interdisciplinary doctoral program created by the School of Medicine in recent years.

School officials say the fact that the university is taking the rare step of creating a new doctoral program acknowledges the growing importance of stem cell research in the realm of biomedical science. The senate’s initial approval
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Stem cells from aged, damaged hearts could be used to treat heart failure

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A new research has suggested that cardiac stem cells – even in elderly and sick patients – could generate new heart muscle and vessel tissue and be used to treat heart failure.

Scientists surgically removed tissue from the muscular wall of the heart’s chambers in 21 patients.

They then isolated and multiplied the cardiac stem cells (CSCs) found there.

Most of the patients had ischemic cardiomyopathy (enlarged and weakened muscle due to coronary artery disease). Eleven also had diabetes. The average age of patients was about 65.

“Regardless of the gender or age of the patient, or of diabetes, we were
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Professor Martin Elliott on Ciaran Finn-Lynch’s return home

“The tracheal team at Great Ormond Street Hospital is delighted that Ciaran is going home after his tracheal transplant. He is a wonderful boy who has become a great friend to us all, and he and his infinitely patient family have charmed us all. Ciaran has become our local iPad expert, and we will miss his advice. His recovery has been complicated, as one might expect for a new procedure, and we have kept him under close surveillance, hence the length of time he has been here. It is wonderful to see him
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Stem cell research aids understanding of cancer

An international team of researchers led by renowned stem cell scientist Professor Martin Pera has discovered a novel marker that plays an important role in our understanding of how cancer develops in the liver, pancreas and oesophagus.

The study, published in the journal Stem Cell, adds to our understanding of the role of stem and next stage progenitor cells in tissue regeneration and in the diagnosis and treatment of cancer.

While stem cells are known to reside in organs such as the liver and pancreas, they are difficult to isolate. The new findings show that an antibody developed by the team
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