Scientists have for the first time watched and manipulated stem cells as they regenerate tissue in an uninjured mammal, Yale researchers report July 1 online in the journal Nature.
Using a sophisticated imaging technique, the researchers also demonstrated that mice lacking a certain type of cell do not regrow hair. The same technique could shed light on how stem cells interact with other cells and trigger repairs in a variety of other organs, including lung and heart tissue.
“This tells us a lot about how the tissue regeneration process works,” said Valentina Greco, assistant professor of genetics and of dermatology at
An international team of researchers led by renowned stem cell scientist Professor Martin Pera has discovered a novel marker that plays an important role in our understanding of how cancer develops in the liver, pancreas and oesophagus.
The study, published in the journal Stem Cell, adds to our understanding of the role of stem and next stage progenitor cells in tissue regeneration and in the diagnosis and treatment of cancer.
While stem cells are known to reside in organs such as the liver and pancreas, they are difficult to isolate. The new findings show that an antibody developed by the team
A new biomaterial that enhances the ability of stem cells to regenerate into nerves and body parts has been developed by Australian and British scientists.
The work was a result of a joint study undertaken by the researchers at the Melbourne-based Monash University and UK-based University of Warwick.
Other biomedical “scaffold” materials, which act as templates for tissue regeneration, already exist but they cannot communicate effectively with the cells they are trying to influence.
The researchers have created a more advanced material that targets specific cells and provides clear signals to these cells to enhance regeneration.