Tag Archives: Progenitor cell

Stem cells may improve the adaptability of dental implants

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A procedure using stem cells may provide a more thorough regeneration of periodontal tissue around dental implants, according to a new report published in the Journal of Oral Implantology.

Dental implants closely resemble natural teeth, but an implant’s ability to react to patient growth, pressure from chewing, and future orthodontic work is diminished if it is not surrounded by sufficient periodontal tissue.

In this study, the authors engineered this periodontal tissue in a fresh socket of a goat animal model. Each of five goats was fitted with two titanium implants immediately after tooth removal. A poly DL-Lactide-co-Glycolide scaffold was
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Male Pattern Balding May Be Due to Stem Cell Inactivation

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Given the amount of angst over male pattern balding, surprisingly little is known about its cause at the cellular level. In a new study, published in the Journal of Clinical Investigation, a team led by George Cotsarelis, MD, chair of the Department of Dermatology at the University of Pennsylvania School of Medicine, has found that stem cells play an unexpected role in explaining what happens in bald scalp.

Using cell samples from men undergoing hair transplants, the team compared follicles from bald scalp and non-bald scalp, and found that bald areas had the same number of stem cells
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Master Switch for Myelination in Brain Stem Cells

“Now that we have identified SOX10 as an initiator of myelination, we can work on developing a viral or pharmaceutical approach to inducing it in MS patients,” says Fraser J. Sim, PhD, assistant professor and senior author of the paper.

Transcription factors are proteins or molecules that bind to DNA and alter which genes are turned on, or expressed.

“If we could create a drug that would switch on SOX10, that would be therapeutically important,” Sim explains.
Removing Barriers to MS Stem Cell Therapy

Targeting SOX10 offers hope for a viable stem cell treatment for MS.

Long seen as having dramatic potential for treating
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Macular Degeneration: Awesome results from Stem Cells

CHA Bundang Medical Center has become the first in Asia (the second in the world) to confirm that the transplantation of human embryonic stem cell (hESC)-derived retinal pigment epithelium (RPE) cells is effective in treating age-related macular degeneration (AMD) and Stargardt disease (juvenile macular degeneration) without causing dangerous side effects. Hence CHA Bundang Medical Center is now on the fast track to developing the world’s first hESC-based therapeutic product.

A Korean research team, led by Professor Song Won-Kyung from CHA Bundang Medical Center, and CHA Biotech (a leading S. Korea-based biotechnology firm focused on stem cell therapies) jointly issued an
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Wisconsin Stem Cell Symposium to focus on blood

World stem cell leaders will converge on Promega’s BioPharmaceutical
Technology Center in Fitchburg, Wisconsin, on April 30 for the 9th
Annual Wisconsin Stem Cell Symposium: From Stem Cells to Blood.

Coordinated by the nonprofit BioPharmaceutical Technology Center Institute, the University of Wisconsin-Madison Stem Cell and Regenerative Medicine Center
and the UW-Madison Blood Research Program, this year’s symposium is
focused on how the stem cells that give rise to blood develop and
function.

It will also look at the diversity of insights stem cell
studies have provided other fields.

Highlighted topics include genesis and regulation of progenitor cells
and hematopoietic stem cells, stem cell genomes/epigenomes, stem cell
microenvironment, and tumor initiating
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