Surgeons in Sweden have replaced the cancerous windpipe of a Maryland man with one made in a laboratory and seeded with the man’s cells.
The windpipe, or trachea, made from minuscule plastic fibers and covered in stem cells taken from the man’s bone marrow, was implanted in November.
The patient, Christopher Lyles, 30, whose tracheal cancer had progressed to the point where it was considered inoperable, arrived home in Baltimore on Wednesday. It was the second procedure of its kind and the first for an American.
“I’m feeling good,” Lyles said in a telephone interview. “I’m just thankful for a second chance
Ciaran Finn-Lynch, who became the first child in the world to undergo a groundbreaking trachea transplant in March this year, is set to return home to Northern Ireland.
Ciaran underwent the transplant, which involved the removal of his own trachea replaced by a donor windpipe, at Great Ormond Street Hospital. Doctors then used Ciaran’s own stem cells from inside his body to build up the donor windpipe and ensure the organ was not rejected.
Four weeks ago, doctors were able to describe the transplant as a success for the first time after proving vascular supply had returned to
Pier Paolo Parnigotto with Mariateresa Conconi
After a trachea transplant that was not rejected, performed in Barcelona by Italian surgeon Paolo Macchiarini, soon other organs and biotech tissues will be reconstructed in the lab thanks to a technique developed by the University of Padova. Bones, livers, the esophagus, pancreases, and muscles will be next, in research that will possibly take place in the Veneto. According to Pierpaolo Parnigotto, 61 year old professor of anatomy, who together with Maria Teresa Conconi carried out tissue engineering research for 15 years in the development of biotech organ grafts that