A new report brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a “scaffolding” material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection.
In a medical first, University researchers have created a beating heart in the laboratory. Using detergents, they stripped away the cells from rat hearts until only the nonliving matrix, or “skeleton,” was left; they then repopulated the matrix with fresh heart cells.
If perfected, the technique may be used someday to generate new hearts for patients. In the United States alone, about 5 million people live with heart failure, 550,000 new cases are
It raises hopes that kidney disease patients will one day be able to grow their own new organs with no risk of rejection.
Kidneys 5mm long – the size of those in foetuses – were made using a combination of cells from amniotic fluid, which surrounds babies in the womb, and animal foetal cells.
It is hoped the organs could be grown to maturity if implanted in a patient. In future, people’s amniotic fluid could be retained at birth, allowing it to be used later if they develop kidney disease.
‘The idea is to start with human