In a fresh demonstration of science’s newfound ability to alter the basic units of human life, researchers at the Medical College of Wisconsin have turned the cells in human skin into those in the liver, work that opens new avenues for treating diseases of the liver without relying on organ transplants.
Professor and stem cell researcher Stephen A. Duncan and other scientists in his lab reported this week in the journal Hepatology that they have created reprogrammed mouse liver cells that were identical to those grown in nature and were able to integrate and grow alongside those in a mouse
A new report brings bioengineered organs a step closer, as scientists from Stanford and New York University Langone Medical Center describe how they were able to use a “scaffolding” material extracted from the groin area of mice on which stem cells from blood, fat, and bone marrow grew. This advance clears two major hurdles to bioengineered replacement organs, namely a matrix on which stem cells can form a 3-dimensional organ and transplant rejection.
From left to right: A normal pig heart, a pig heart after being decellularised, the pig heart prepared for recellularisation. Photos courtesy of the University of Minnesota.
In a medical first, University researchers have created a beating heart in the laboratory. Using detergents, they stripped away the cells from rat hearts until only the nonliving matrix, or “skeleton,” was left; they then repopulated the matrix with fresh heart cells.
If perfected, the technique may be used someday to generate new hearts for patients. In the United States alone, about 5 million people live with heart failure, 550,000 new cases are
The Ospedali Riuniti of Bergamo is the top center for the collection of umbilical cord blood in the Lombardy region, said the hospital, which received an award at the Policlinico di Milano (where the umbilical cord blood bank is located) for the second consecutive year for its commitment and professionalism with which it carries out its work, providing an important source of stem cells.
“Our collection program started in 2004,” explained Bruna Pasini, the head obstetrician, also in charge of the collection of umbilical cord blood for the hospital. “At that time we started to collaborate with the Milano
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The regional transplant center realized by the San Camillo-Forlanini Hospital along with the Spallanzani medical center is attempting to improve the efficiency of organ transplants with the use of stem cells removed from and used in the patient (autologous stem cells). The project designed by the Lazio based medical institutes is currently being used in experiments at the Ospedali Riuniti di Bergamo (United Hospitals of Bergamo). Rejection is the most frequent cause of kidney transplant failure. With current anti-rejection drugs, about 50% of kidney transplants stop functioning after about 10 years due to chronic