The Pisa University Hospital has become part of the international network of hematopoietic stem cell transplant facilities (meaning they produce various blood components). The hospital was recently accredited by the Italian registry of bone marrow donors, which is part of the international network.
Pisa has become an important center for bone marrow collection for all potential donors in northwestern Italy.
On 20 April 2009, the first donation was carried out for a patient at the Udine University Hospital, and a second donation is being organized for a patient being treated at the Montpellier Hospital (France).
The hospital in Pisa received the
December 4, 2009- Working with mice, scientists at Johns Hopkins publishing in the December issue of Neoplasia have shown that a protein made by a gene called “Twist” may be the proverbial red flag that can accurately distinguish stem cells that drive aggressive, metastatic breast cancer from other breast cancer cells.
Building on recent work suggesting that it is a relatively rare subgroup of stem cells in breast tumors that drives breast cancer, scientists have surmised that this subgroup of cells must have some very distinctive qualities and characteristics.
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Oncologists are now faced with the challenge of understanding how specialized drugs can strike tumor stem cells and impair their ability to replicate and spread. This is one of the most important questions that researchers will have to answer in upcoming years according to Regina Elena Institute hematologist Michele Milella. In San Francisco at the American Society of Hematology (ASH) Congress Milella spoke about future hematology issues, including fighting blood borne tumors with stem cell transplants over the past years.
“The ASH in this sense is an excellent indicator for where research is going, and
The first operations have been successfully performed at Seriate Hospital (Bergamo) using autologous stem cell transplants to rebuild a part of the breast after removing a tumor. The technique used in the operation is known as ‘lipofilling’, which calls for some of the patient’s abdominal fat to be removed in a procedure similar to liposuction. The fat is then purified and manipulated in the laboratory to concentrate stem cells as much as possible, then they are transplanted into the portion of the breast that has been removed to eliminate the cancer.
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Scientists at the FIRC (Italian Foundation for Cancer Research) Institute of Molecular Oncology of the European Institute of Oncology in Milan have revealed how to eliminate cancer stem cells, the true reason for cancer’s incurability. Researchers led by Pier Giuseppe Pelicci, Director of the Department of Experimental Oncology of the European Institute of Oncology, and Professor of general pathology at the University of Milan, have discovered how cancer stem cells become immortal.
The same oncogenes that are responsible for triggering the process of tumor formation, also impede stem cells from growing old, and allow them to maintain their