A new treatment regimen can help some patients who have blood cancer to live disease-free longer, University of Floridaresearchers and colleagues have found.
Low doses of a drug called lenalidomide can help hold off the return of multiple myeloma after bone marrow transplantation. Patients who took the drug to maintain health also lived longer than those who did not take the drug.
“In choosing maintenance therapy we look at a few things,” said study co-author Dr. Jan S. Moreb, clinical director of hematologic malignancies in the UF College of Medicine’s division of hematology/oncology and a member of the UF Shands Cancer
Children born with so-called “bubble boy” disease have the best chance of survival if they undergo a hematopoietic stem cell transplant as soon after birth as possible, according to a detailed analysis of 10 years of outcome data by researchers at the Harvard-affiliated Dana-Farber/Boston Children’s Cancer and Blood Disorders Center.
Researchers say the findings support expanding newborn screening for severe combined immune deficiency (SCID), a disorder that leaves affected infants so vulnerable to infection that most die within the first year of life if untreated.
The study, published today in the New England Journal of Medicine, analyzed data on 240 children
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It was stunning to see them closed inside of those plastic bubbles, kept far from all external contact because their immune system does not react against any foreign antigens. Today scientists can say that ADA-SCID (adenosine deaminase deficiency), a serious combined immunodeficiency caused due to a lack of the adenosine deaminase enzyme, has been definitively defeated by gene therapy developed at San Raffaele of Milan.
The final study, which combined the conclusions of clinical studies, which began in 2000 on strategic therapies developed by the HSR-TIGET (San Raffaele Telethon Institute for Gene Therapy) group,
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Numerous studies performed by various scientific teams throughout the world, including the National Institute of Health have clearly established that the higher the levels of circulating stem cells the better the ability of the body to maintain optimal health.
A recent publication in the New England Journal of Medicine reported that the level of stem cells in the blood was one of the best indicators of cardiovascular health. Elevating the number of
For the first time, researchers at Brigham and Women’s Hospital (BWH) have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung including bronchioles, alveoli and pulmonary vessels. This research is published in the May 12, 2011 issue of the New England Journal of Medicine.
“This research describes, for the first time, a true human lung stem cell. The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the