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Memorial Hermann-Texas Medical Center in Houston announced this morning it has done the nation’s first stem cell transplant to successfully treat a stroke patient.
The patient came to the hospital last Wednesday, too late to receive clot-busting drugs to treat the stroke, according to a news release about the procedure. So doctors decided to try a therapy they are investigating as part of a clinical trial with the University of Texas Medical School at Houston: using stem cells from the patient’s own bone marrow. The adult stem cells — not controversial embryonic stem cells — came from marrow
StemCells Inc. announced preclinical data demonstrating that its proprietary human neural stem cells restored memory and enhanced synaptic function in two animal models relevant to Alzheimer’s disease (AD). The data was presented today at the Alzheimer’s Association International Conference 2012 in Vancouver, Canada.
The study results showed that transplanting the cells into a specific region of the brain, the hippocampus, statistically increased memory in two different animal models. The hippocampus is critically important to the control of memory and is severely impacted by the pathology of AD. Specifically, hippocampal synaptic density is reduced in AD and correlates with memory loss.
Hans Keirstead, a researcher at University of California, Irvine, is set to begin a small human trial of his embryonic stem cell treatment on patients with spinal cord injuries. The treatment is designed for patients within 14 days of suffering spinal cord injuries. In rat trials, paralyzed rats were injected with a stem cell formula. The paralyzed rats were able to walk six weeks later.
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New hope in treating Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s Disease, an incurable neurological disease, which is particularly frequent in former soccer players, may come from stem cells. Nicholas Maragakis and his colleagues from the Johns Hopkins University of Medicine in Baltimore in the United States, have successfully conducted an important experiment in mice. In a study published in the online edition of ‘Nature Neuroscience’, the American researchers transplanted precursor cells called astrocytes, which function as support cells for neurons, into the mice with ALS. This allow the mice to survive for much longer.
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Dr. Feng Lin, Director of Research at Bio-Matrix Scientific Group Inc. (OTCBulletinBoard: BMSN) and Entest BioMedical Inc., today stated that he believes that an effective new therapy for “traumatic brain injury” (TBI) using autologous “adipose-derived” stem cells represents a potential cure for TBI. According to Dr. Lin, both Bio-Matrix and Entest BioMedical are now studying the “therapeutic effect of fat stem cells on traumatic brain injury-associated brain ischemia and inflammation and replacement of damaged neurons with neuron cells differentiated from fat cells.” Bio-Matrix Scientific Group Inc. and Entest BioMedical Inc. recently submitted a research summary