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Perhaps in the not-too-distant future people who need “to rebuild” their prostate will be able to do so using stem cells removed from prostate tissue. This week Nature magazine reported that a group of Genetech researchers in San Francisco has isolated stem cells extracted from prostate tissue of an adult mouse and used them to generate new prostate cells in the same rat. Wei-Qiang Gao, the coordinator of the study, described the factors that made these cells, which are able to regenerate on a long term basis.
In the same study, researchers reported that they
Andreas Trumpp and his colleagues from the German Cancer Research Center have recently spoken about a “silent reserve” of stem cells, wondering what type of medical impact the discovery made in Heidelberg of “dormant stem cells” could have.
Usually, dormant bone marrow cells activate and multiply only in a crisis or emergency to react to serious cellular loss due to a virus or hemorrhage. When their work is done, they return to a dormant stage. This withdrawal phase keeps them protected from mutations, cellular toxins, and other dangerous substances, since the cells do not divide
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UW-Milwaukee researcher Andrew Cohen has successfully developed a software program that facilitates predicting the evolution of stem cells. The program essentially speeds up what has been a tedious process for researchers in the past.
The program was published last week in the journal Nature Methods. It applies algorithmic information theory to the growth and movement of stem cells tracked over time to show what type of cells (i.e. brain, skin, etc.) they will eventually develop into.
“People look at images and take measurements by hand,” Cohen explained. “It takes a long time, and using computers makes the process a
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Artificial intestines could be created thanks to stem cells. Intestinal stem cells grown in the laboratory have been manipulated to differentiate in order to produce all of the different types of cells that form intestinal epithelium, said a Dutch study, published in ‘Nature’ magazine by Hans Clevers of the Hubrecht Institute in Utrecht.
The study also outlines a more precise link between stem cells and their microenvironment.
It also offers a practical technique to generate new intestinal epithelium in the laboratory. Stem cells, which express the Lgr5 protein, were discovered on several specific regions of
Scientists have for the first time watched and manipulated stem cells as they regenerate tissue in an uninjured mammal, Yale researchers report July 1 online in the journal Nature.
Using a sophisticated imaging technique, the researchers also demonstrated that mice lacking a certain type of cell do not regrow hair. The same technique could shed light on how stem cells interact with other cells and trigger repairs in a variety of other organs, including lung and heart tissue.
“This tells us a lot about how the tissue regeneration process works,” said Valentina Greco, assistant professor of genetics and of dermatology at