Scientists said on Monday they had used cloning technology to make embryonic stem cells that carry a diabetic woman’s genes, and turned them into insulin-producing beta cells that may one day cure her disease.
The team reported clearing an important hurdle in the quest to make “personalised stem cells” for use in disease therapy, but a bioethicist said the breakthrough also highlighted the need for better regulation of lab-grown embryos.
“We are now one step closer to being able to treat diabetic patients with their own insulin-producing cells,” said Dieter Egli of the New York Stem Cell Foundation (NYSCF), who led
Researchers from the University of Cambridge have created mammalian cells containing a single set of chromosomes for the first time in research funded by the Wellcome Trust and EMBO. The technique should allow scientists to better establish the relationships between genes and their function.
Mammal cells usually contain two sets of chromosomes – one set inherited from the mother, one from the father. The genetic information contained in these chromosome sets helps determine how our bodies develop. Changes in this genetic code can lead to or increase the risk of developing disease.
To understand how our genes function, scientists manipulate the
“Generation of a synthetic retina from embryonic stem cells is a landmark discovery that will help enormously our understanding of blinding eye disease” (Professor James Bainbridge of Moorfields Eye Hospital NHS Foundation Trust)
A part of the eye that is essential for vision has been created in the laboratory from animal stem cells, offering hope to the blind and partially sighted.
One day it might be possible to make an eye in a dish, Nature journal reports.
The Japanese team used mouse stem cells – immature cells that have the ability to turn into many types of body tissue (…)