Scientists have for the first time watched and manipulated stem cells as they regenerate tissue in an uninjured mammal, Yale researchers report July 1 online in the journal Nature.
Using a sophisticated imaging technique, the researchers also demonstrated that mice lacking a certain type of cell do not regrow hair. The same technique could shed light on how stem cells interact with other cells and trigger repairs in a variety of other organs, including lung and heart tissue.
“This tells us a lot about how the tissue regeneration process works,” said Valentina Greco, assistant professor of genetics and of dermatology at
Dr. Karen Aboody estimates that she has cured several hundred mice of a cancer of the central nervous system called neuroblastoma.
First she injected them with specialized neural stem cells that naturally zero in on the tumors and surround them. Then she administered an anti-cancer agent that the cells converted into a highly toxic drug (…)
For 3 1/2 years, the agency focused on the basic groundwork needed to someday use human embryonic stem cells to replace body parts damaged by injury or disease. Such cures are still far in the future.
Now the institute has a more immediate goal: boosting therapies
For the first time, researchers at Brigham and Women’s Hospital (BWH) have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung including bronchioles, alveoli and pulmonary vessels. This research is published in the May 12, 2011 issue of the New England Journal of Medicine.
“This research describes, for the first time, a true human lung stem cell. The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the
I just had a birthday, and to honor such occasions, my sister always gives me silver. Not just any silver: It’s our parents’ simple wedding flatware pattern, which Margaret collects for me, one piece at a time. Over the years that the slender boxes have appeared, I’ve wondered if any of it is from the full service for 12 that I pulled in a suitcase through Manhattan’s Diamond District and sold one dreadful day 25 years ago.
It had been my assignment to sell it —- that, and a ring of Margaret’s, one of mine and, right off our mother’s