Tag Archives: National Institutes of Health

Human Lung Stem Cell Discovered

For the first time, researchers at Brigham and Women’s Hospital (BWH) have identified a human lung stem cell that is self-renewing and capable of forming and integrating multiple biological structures of the lung including bronchioles, alveoli and pulmonary vessels.  This research is published in the May 12, 2011 issue of the New England Journal of Medicine.

“This research describes, for the first time, a true human lung stem cell.  The discovery of this stem cell has the potential to offer those who suffer from chronic lung diseases a totally novel treatment option by regenerating or repairing damaged areas of the
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Don’t sell out on stem cell research

I just had a birthday, and to honor such occasions, my sister always gives me silver. Not just any silver: It’s our parents’ simple wedding flatware pattern, which Margaret collects for me, one piece at a time. Over the years that the slender boxes have appeared, I’ve wondered if any of it is from the full service for 12 that I pulled in a suitcase through Manhattan’s Diamond District and sold one dreadful day 25 years ago.

It had been my assignment to sell it —- that, and a ring of Margaret’s, one of mine and, right off our mother’s
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Research identifies protein that regulates creation of fat cells

Biological sciences major Adam Reese may have found the key to keep fat cells from forming.

The University of Delaware junior believes he has identified the trigger that turns a stem cell into a fat cell. Located on the surface of cells, the trigger — a protein called endoglin — regulates what type of cell an existing stem cell will become.

Working in the UD Department of Biological Sciences‘ laboratory of cellular signaling and dynamics with assistant professor Anja Nohe, Reese investigates ways to combat osteoporosis. His findings may also have implications for obesity.

Patients afflicted with osteoporosis lose bone mass as
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UCLA-engineered stem cells seek out and kill HIV in living organisms

Expanding on previous research providing proof-of-principle that human stem cells can be genetically engineered into HIV-fighting cells, a team of UCLA researchers has now demonstrated that these cells can actually attack HIV-infected cells in a living organism.

The study, published April 12 in the journal PLoS Pathogens, demonstrates for the first time that engineering stem cells to form immune cells that target HIV is effective in suppressing the virus in living tissues in an animal model, said lead investigator Scott G. Kitchen, an assistant professor of medicine in the division of hematology and oncology at the David Geffen School of
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Scientists Aim to Use Embryonic Stem Cells for Chronic Pain

Chronic pain, by definition, is difficult to manage, but a new study by UCSF scientists shows how a cell therapy might one day be used not only to quell some common types of persistent and difficult-to-treat pain, but also to cure the conditions that give rise to them.

The researchers, working with mice, focused on treating chronic pain that arises from nerve injury — so-called neuropathic pain.

In their study, published in the May 24, 2012 issue of Neuron, the scientists transplanted immature embryonic nerve cells that arise in the brain during development and used them to make up for a
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