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In the near future, hearts that have just suffered a heart attack will be able to repair themselves, according to an incredible discovery of how to reeducate cardiac stem cells to repair damaged hearts. In fact, stem cells normally perform the delicate task of repairing cardiac muscle, but after a heart attack the cells no longer carry out this highly important self-repair.
Italian scholars at the ‘Sapienza’ University in Rome and the European Molecular Biology Laboratory (EMBL) in Monterotondo, have discovered why these cells stop functioning correctly, and now understand how to induce them to
Fat around the waist is commonly seen as a contributing factor to heart attack. Ironically, a company is now testing whether adult stem cells from fat could help prevent long-term damage after a heart attack.
A new medical team is now investigating whether adult stem cells harvested from a person’s own fat, delivered shortly after a heart attack, could prevent some of the cardiac muscle damage that results from blocked arteries.
During a heart attack, blood vessels that deliver blood to the heart muscle are blocked. The lack of oxygen slowly kills the tissue. San Diego-based Cytori Therapeutics has developed
Harvard Stem Cell Institute (HSCI) scientists collaborating with researchers at the University of Pennsylvania have developed a “genome-editing” approach for permanently reducing cholesterol levels in mice through a single injection, a development that could reduce the risk of heart attacks in humans by 40 to 90 percent.
“For the first iteration of an experiment, this was pretty remarkable,” said Kiran Musunuru of HSCI, an assistant professor in Harvard’s Department of Stem Cell and Regenerative Biology (SCRB), and a cardiologist at Harvard-affiliated Brigham and Women’s Hospital. Musunuru stressed, however, that it could take a decade of concerted effort to get this
Concha Herrera Arroyo, from El Pais
The Cardiology department and the Area of Cell Therapy of Cordoba hospital Reina Sofia are carrying out clinical tests with patients who have suffered from a severe heart attack. With the implantation of the patient’s stem cells, the heart regenerates thus improving its wall motion, that is, its cardiac performance.
Indeed for the last four years, the Area of Cell Therapy of Cordoba hospital, led by haematologist Dr. Concha Herrera, has been implementing a therapy program with adult stem cells in patients with heart-related problems. However, this therapy is not a service the hospital
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A new research has suggested that cardiac stem cells – even in elderly and sick patients – could generate new heart muscle and vessel tissue and be used to treat heart failure.
Scientists surgically removed tissue from the muscular wall of the heart’s chambers in 21 patients.
They then isolated and multiplied the cardiac stem cells (CSCs) found there.
Most of the patients had ischemic cardiomyopathy (enlarged and weakened muscle due to coronary artery disease). Eleven also had diabetes. The average age of patients was about 65.
“Regardless of the gender or age of the patient, or of diabetes, we were