Tag Archive for 'Mutation'

Berlin, Germany – Stem cell transplant cures HIV in patient

Stem cell transplantation in a 42-year-old HIV patient with leukemia has wiped out the virus from his body, the doctor of Berlin Charité Hospital confirms.
The patient is fine,” said Dr. Gero Hutter, a haematologist at the Berlin Charité Hospital. “Today, two years after his transplantation, he is still without any signs of HIV disease and without antiretroviral medication.”

The doctor observed that using the stem cells from a donor who carries a unique gene mutation i.e. delta 32 ccr5 along with a tissue match, could now cure the patient from the HIV virus. Delta 32 ccr5 makes the cells resistant to HIV virus and this mutation is found in a little more than 1 percent of Caucasians.
Dr. Hutter told, “When the recipient got the new bone marrow, his cells could now block out the HIV, and, in effect, he was cured. Bone marrow transplants are high risk, so only lymphoma and leukemia patients take the risk to possibly cure their cancer.”

The study is published Wednesday in the New England Journal of Medicine.

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