Tag Archives: MIT

New coating for hip implants could prevent premature failure

Hip-Joint, total Replacement, insertion without bone-cement (Photo credit: Wikipedia)

Nanoscale films developed at MIT promote bone growth, creating a stronger seal between implants and patients’ own bone.

Every year, more than a million Americans receive an artificial hip or knee prosthesis. Such implants are designed to last many years, but in about 17 percent of patients who receive a total joint replacement, the implant eventually loosens and has to be replaced early, which can cause dangerous complications for elderly patients.

To help minimize these burdensome operations, a team of MIT chemical engineers has developed a new coating for implants that could
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MIT team’s nanoparticles could become a safer alternative to gene therapy delivered by viruses

About five years ago, Professor Janet Sawicki at the Lankenau Institute in Pennsylvania read an article about nanoparticles developed by MIT’s Daniel Anderson and Robert Langer for gene therapy, the insertion of genes into living cells for the treatment of disease. Sawicki was working on treating ovarian cancer by delivering — through viruses — the gene for the diphtheria toxin, which kills tumor cells (…)