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Stem cell researcher Dr. Ann Kiessling announced today the discovery of cell characteristics that may explain important differences between embryonic stem cells and adult stem cells. Scientists have for years been frustrated in their efforts to grow the trillions of adult stem cells needed for therapies, which is why embryonic stem cells seem promising — they can multiply endlessly and also develop into any cell in the body.
Kiessling discovered that early human embryo cells express CLOCK, and other circadian genes, that other human cells growing in laboratories did not. This was a surprise. Although scientists have recently become aware that human tissues have a circadian oscillator that cycles every 24 hours, in phase with the master circadian pacemaker in the brain that responds to light and dark, early embryos seemed too small to function like a tissue.
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