“Generation of a synthetic retina from embryonic stem cells is a landmark discovery that will help enormously our understanding of blinding eye disease” (Professor James Bainbridge of Moorfields Eye Hospital NHS Foundation Trust)
A part of the eye that is essential for vision has been created in the laboratory from animal stem cells, offering hope to the blind and partially sighted.
One day it might be possible to make an eye in a dish, Nature journal reports.
The Japanese team used mouse stem cells – immature cells that have the ability to turn into many types of body tissue (…)
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Scientists genetically “reprogrammed” human skin cells to possess the same properties as those that make up the retina.
The process involved first turning them into pluripotent stem (IPS) cells, which have the potential to develop into virtually every kind of tissue in the body.
By exposing the IPS cells to a specific cocktail of chemicals, the scientists then caused them to grow into partially developed retina cells – the light-sensitive cells at the back of the eye which transmit nerve signals to the brain.
Although the work, published in the Proceedings of the National Academy of Sciences, is
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Human embryonic stem cells implanted into mice specifically engineered to have a serious retinal dysfunction resulting in blindness have restored the animal’s capacity to sense light during tests.
The results, published in international magazine, Cell Stem Cell, were obtained in the United States by a research group in the Department of Biological Structure at the University of Washington in Seattle. The study, performed by Deepak Lamba, Juliane Gust, and Thomas Reh, demonstrated that it is possible to obtain retina progenitor cells from stem cells derived from the embryo. The researchers observed, “In principle, embryonic stem
Discover StemCells, Inc. A pioneer in the field of neural stem cells, StemCells Inc was founded by the renown Irving Weissman, Fred Gage, and David Anderson. Martin McGlynn, CEO, presents StemCells Inc’s use of neural stem cells, and clinical development strategy based on the neuroprotective effect of neural stem cells.
Stem Cells Inc is preparing a BLA for NCL (a.k.a. Batten’s Disease). Martin reveals the source of the stem cells used, as well as the quantity of cells needed for the treatment of various diseases. StemCells Inc’s next clinical trials (PMD, spinal cord, macular degeneration) and milestones are also presented
An Iranian scientist managed to develop a new method to propagate human spermatogonial stem cells from small testicular biopsies to obtain adequate number of cells for successful transplantation for 18000-fold in vitro, leading to protection of the fertility of immature boys suffering from cancer.
The research carried out jointly with Amsterdam University in Holland is the first developed method in the world.
Hooman Sadri-Ardekani, Ph.D in Reproductive Medicine and a Professor in Avicenna Institute-ACECR told ISNA, “Young boys treated with high-dose chemotherapy are often confronted with infertility once they reach adulthood and cryopreserving testicular tissue before chemotherapy and auto transplantation of