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New hope in treating Amyotrophic Lateral Sclerosis (ALS) or Lou Gehrig’s Disease, an incurable neurological disease, which is particularly frequent in former soccer players, may come from stem cells. Nicholas Maragakis and his colleagues from the Johns Hopkins University of Medicine in Baltimore in the United States, have successfully conducted an important experiment in mice. In a study published in the online edition of ‘Nature Neuroscience’, the American researchers transplanted precursor cells called astrocytes, which function as support cells for neurons, into the mice with ALS. This allow the mice to survive for much longer.
Advancements in stem cell research may one day help surgeons provide treatment for Amyotrophic Lateral Sclerosis (ALS), also known as Lou Gehrig’s disease, a deadly neurodegenerative disease characterized by the selective death of motor neurons.
CD133+ stem cells are known to have the capacity to differentiate into neural lineages and may provide an alternative treatment for patients suffering from ALS and other neurodegenerative diseases.
According to Newswise, Linda Kelley, Ph.D., director of the University of Utah’s Cell Therapy Facility, James Campanelli, Ph.D., of University of Utah spin-out Q Therapeutics, Inc., and Utah native Nicholas Maragakis, M.D., of The Johns Hopkins University
What is a neural stem cell? How can they help treat neurological disorders such as Alzheimer’s disease, Parkinson’s disease, spinal cord injury, stroke, ALS (Lou Gehrig‘s Disease)? Evan Snyder of the Burnham Institute helps define neural stem cells (NSC), explaining that they are relatively inaccessible in the adult patient, but that they seem to benefit from some immunotolerance.
It follows that we may be able to use readily available lines of embryonic stem cells for therapy in neurodegenerative disease. Evan reviews current clinical applications for neural stem cells (including as a vehicle for small molecule delivery), and gives his
A revolutionary stem cell procedure may be able to stop ALS, or Lou Gehrig‘s disease, in its tracks.
HealthFirst reporter Leslie Toldo shares the story of one of the few people who have had it done.
ALS is a deadly disease, with a quick and devastating decline. This could be the hope thousands of people have been waiting for.
Fifty-five-year-old Tom Elliott is not a quitter. He has ALS and fights to keep up with the daily routines of his life, even as the disease makes everything harder. “Brushing the teeth has become a real chore. Turning and rolling in bed to
A recent scientific follow-up study of patients who underwent autologous stem cell therapy for amyotrophic lateral sclerosis, or Lou Gehrig‘s disease, has proved the effectiveness of the therapy. Returning Hope, in Thailand, is one of the first Asian health care providers to arrange for this type of stem cell treatment.
The follow up study was conducted by a team from Akay Hospital, GATA, the University of Marmara, and the Sila Neurorehabilitation Center. It followed 13 patients for one year after stem cell treatment for ALS.
Participants in the study had the following outcomes:
Nine of thirteen participants had significant improvement, proven by