Tag Archives: LA JOLLA

Stem cells defeat multiple sclerosis

Mouse severely disabled by a condition similar to multiple sclerosis (MS) could walk less than two weeks following treatment with human stem cells.

When scientists transplanted human stem cells into MS mice, they expected no benefit from the treatment. They thought the cells would be rejected, much like rejection of an organ transplant.

Instead, the experiment yielded spectacular results.

Within a short period of time, 10 to 14 days, the mice could walk and run. Six months later, they showed no signs of slowing down.

Isolating breast stem cells speeds cancer research

LA JOLLA—By carefully controlling the levels of two proteins, researchers at the Salk Institute have discovered how to keep mammary stem cells—those that can form breast tissue—alive and functioning in the lab. The new ability to propagate mammary stem cells is allowing them to study both breast development and the formation of breast cancers.

“What we’ve shown is that we can take these cells out of a mouse and study them and regulate them in the laboratory by providing them with a specific factor,” says Peter C. Gray, a staff scientist in Salk’s Clayton Foundation Laboratories for Peptide Biology, who
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Transplants: human-pig embryos from stem cells

Scientists have for the first time grown embryos that contain a combination of pig and human stem cells, in a step toward one day growing transplantable organs, a study said on Thursday.

However, the research remains at a very early stage and proved more difficult than expected, the researchers reported in the peer-reviewed journal Cell.

“This is an important first step,” said lead investigator Juan Carlos Izpisua Belmonte, a professor in the Salk Institute of Biological Studies’ Gene Expression Laboratory.

“The ultimate goal is to grow functional and transplantable tissue or organs, but we are far away from that.”

Scientists implanted adult human
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